Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5169993 | 1.00 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL6092049 | 0.86 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL6093423 | 0.85 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL214145 | 0.85 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL16914758 | 0.79 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6094518 | 0.77 | NFKB1 (0.43) | PTGS2PTGS1 | |
| SCHEMBL5645071 | 0.77 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL7150453 | 0.77 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL5645779 | 0.76 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL5646666 | 0.76 | PTGS2 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773802-A1 | ENANTIOSELECTIVE METHOD FOR SEPARING SUBSTITUTED 2-TRIFLUOROMETHYL-2H-CHROMENE-3-CARBOXYLIC ACID DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006011047-A1 | ENANTIOSELECTIVE METHOD FOR SEPARING SUBSTITUTED 2-TRIFLUOROMETHYL-2H-CHROMENE-3-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-02 | — | — | WO | disclosed |