Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183100 | 0.89 | ACACB (0.32) | — | |
| SCHEMBL5170212 | 0.87 | BDKRB1 (0.30) | — | |
| SCHEMBL5170769 | 0.83 | SLC18A2 (0.33) | — | |
| SCHEMBL5171053 | 0.82 | HRH3 (0.35) | — | |
| SCHEMBL5183241 | 0.81 | HRH3 (0.33) | — | |
| SCHEMBL5170766 | 0.81 | SMO (0.34) | — | |
| SCHEMBL5170245 | 0.80 | HRH3 (0.35) | — | |
| SCHEMBL5173434 | 0.80 | KDM4C (0.35) | — | |
| SCHEMBL5169168 | 0.78 | PRMT5 (0.37) | — | |
| SCHEMBL5170526 | 0.78 | KCNH2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778643-A1 | TETRAHYDROBENZAZEPINES AS ANTAGONISTS AND/OR REVERSE AGONISTS OF THE HISTAMINE H3 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006018260-A1 | TETRAHYDROBENZAZEPINES AS ANTAGONISTS AND/OR REVERSE AGONISTS OF THE HISTAMINE H 3 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2006-02-23 | — | — | WO | disclosed |