SCHEMBL517074

SCHEMBL517074

CC1CNc2ccccc2O1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.54
CREBBP Q92793 3/20 0.54
NISCH Q9Y2I1 2/20 0.49
HPGD P15428 1/20 0.47
PARP1 P09874 1/20 0.46
CASR P41180 1/20 0.41
GAA P10253 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HTR1A P08908 3/20 0.37
ALOX5 P09917 1/20 0.35
AKR1B1 P15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19392968 1.00 BRD4 (0.54) BRD4CREBBPNISCHHPGDPARP1
Oxalic Acid SCHEMBL27480190 0.90 CREBBP (0.50) BRD4CREBBPNISCHHPGDPARP1
Diethylamine SCHEMBL9700350 0.88 HPGD (0.49) BRD4CREBBPNISCHHPGDPARP1
SCHEMBL8564064 0.77 NISCH (0.46) BRD4CREBBPNISCHHPGDPARP1
SCHEMBL15158184 0.77 HPGD (0.48) BRD4CREBBPNISCHHPGDPARP1
SCHEMBL8564068 0.77 NISCH (0.46) BRD4CREBBPNISCHHPGDPARP1
SCHEMBL1981682 0.77 NISCH (0.46) BRD4CREBBPNISCHHPGDPARP1
SCHEMBL15718086 0.76 NISCH (0.49) BRD4CREBBPNISCHHPGDPARP1
SCHEMBL214287 0.76 NISCH (0.49) BRD4CREBBPNISCHHPGDPARP1
SCHEMBL5165849 0.76 NISCH (0.49) BRD4CREBBPNISCHHPGDPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087635-A1 DIHYDRO BENZOXAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
CN-121574131-A Heterocyclic compounds for insect repellent 勃林格殷格翰动物保健有限公司 2026-02-27 CN disclosed
CN-111763180-B Benzazepine compounds, preparation method and pharmaceutical application thereof 中国医学科学院药物研究所 2023-06-09 CN disclosed
CN-116249704-A Heterocyclic compounds for insect repellent 勃林格殷格翰动物保健美国公司 2023-06-09 CN disclosed
US-20230028644-A1 Low Greenhouse Gas Fuel Compositions BP OIL INTERNATIONAL LIMITED (GB) 2023-01-26 US disclosed
US-11384057-B2 Methods for preparing fuel additives BP OIL INTERNATIONAL LIMITED (GB) 2022-07-12 US disclosed
EP-3414305-B1 FUEL COMPOSITIONS BP OIL INT (GB) 2022-06-15 EP disclosed
US-11339343-B2 Methods for blending fuels BP OIL INTERNATIONAL LIMITED (GB) 2022-05-24 US disclosed
US-11332682-B2 Methods for reducing oxidation BP OIL INTERNATIONAL LIMITED (GB) 2022-05-17 US disclosed
EP-3414303-B1 USES OF ADDITIVES FOR DEMULSIFYING BP OIL INT (GB) 2022-01-26 EP disclosed
EP-0670831-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-09-13 EP disclosed
WO-1995009159-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-04-06 WO disclosed
EP-0511879-B1 Pyrazine derivatives OTSUKA PHARMA CO LTD (JP) 1995-03-22 EP disclosed
EP-0511879-A1 Pyrazine derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-04 EP disclosed
EP-0509845-A1 (+) and (-) enantiomers of 5-aliphatic-6-(benzoxazinyl- or benzothiazinyl)-2,3,4,5-tetrahydropyridazin-3-ones ORTHO PHARMACEUTICAL CORPORATION (US) 1992-10-21 EP disclosed
US-5081242-A Cardiotonic and bronchodilator agents; phosphodiesterase inhibitors ORTHO PHARMACEUTICAL CORPORATION (US) 1992-01-14 US disclosed
EP-0368410-A2 Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation GIST-BROCADES N.V. (NL) 1990-05-16 EP disclosed
US-4766118-A CARDIOTONIC AGENTS, PHOSPHODIESTERASE INHIBITORS ORTHO PHARMACEUTICAL CORPORATION (US) 1988-08-23 US disclosed
EP-0272914-A2 6-Benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones ORTHO PHARMACEUTICAL CORPORATION (US) 1988-06-29 EP disclosed
US-4721784-A MUSCLE RELAXANTS, BRONCHODILATOR AGENTS, CARDIOTONIC AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1988-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384057-B2 Methods for preparing fuel additives POLB, IDH2, TOP2B BRD4 898/4885CREBBP 1130/4885NISCH 1427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.