Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517074 | 0.76 | BRD4 (0.54) | NISCHGAANPSR1HPGDHTR1A | |
| SCHEMBL214287 | 0.76 | NISCH (0.49) | NISCHGAANPSR1HPGDHTR1A | |
| SCHEMBL19392968 | 0.76 | BRD4 (0.54) | NISCHGAANPSR1HPGDHTR1A | |
| SCHEMBL3966534 | 0.76 | NISCH (0.49) | NISCHGAANPSR1HPGDHTR1A | |
| SCHEMBL28265080 | 0.76 | NISCH (0.49) | NISCHGAANPSR1HPGDHTR1A | |
| SCHEMBL28265131 | 0.76 | NISCH (0.49) | NISCHGAANPSR1HPGDHTR1A | |
| SCHEMBL15718086 | 0.76 | NISCH (0.49) | NISCHGAANPSR1HPGDHTR1A | |
| SCHEMBL2638179 | 0.76 | CASR (0.47) | NISCHGAANPSR1HPGDHTR1A | |
| SCHEMBL1756750 | 0.74 | HPGD (0.59) | NISCHHPGDKMT2A | |
| SCHEMBL23920549 | 0.74 | AHR (0.39) | NISCHMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168128-A1 | THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT | Henkel AG & Co. KGaA (DE) | 2023-04-26 | — | — | EP | disclosed |
| US-20230047589-A1 | INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY | ALTOS LABS, INC. | 2023-02-16 | — | — | US | disclosed |
| US-20220347187-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO OPERATING COMPANY LLC | 2022-11-03 | — | — | US | disclosed |
| US-11230542-B2 | Inhibitors of integrated stress response pathway | Praxis Biotech LLC (US) | 2022-01-25 | — | — | US | disclosed |
| CN-101022780-B | Method for rapid hair dyeing | PROCTER & GAMBLE | 2014-11-05 | — | — | CN | disclosed |
| CN-102137653-B | Powdered hair colouring and bleaching compositions | PROCTER & GAMBLE | 2014-09-10 | — | — | CN | disclosed |
| CN-101137345-B | Novel hair coloring compositions for oxidative hair dyeing | PROCTER & GAMBLE | 2012-10-31 | — | — | CN | disclosed |
| CN-102137653-A | Powdered hair colouring and bleaching compositions | PROCTER & GAMBLE | 2011-07-27 | — | — | CN | disclosed |
| CN-101848695-A | Oxidative hair colorant compositions | PROCTER & GAMBLE | 2010-09-29 | — | — | CN | disclosed |
| CN-100569212-C | Hair colouring compositions | PROCTER & GAMBLE (US) | 2009-12-16 | — | — | CN | disclosed |
| CN-1486172-A | Primary intermediates for oxidative dyeing of hair | P&G | 2004-03-31 | — | — | CN | disclosed |
| CN-1486170-A | Novel couplers for use in oxidative hair dyeing | P&G | 2004-03-31 | — | — | CN | disclosed |
| CN-1477948-A | Novel couplers for oxidative hair dyeing | P&G克莱罗尔公司 | 2004-02-25 | — | — | CN | disclosed |
| CN-1477947-A | Primary intermediates for oxidative dyeing of hair | P&G | 2004-02-25 | — | — | CN | disclosed |
| CN-1474679-A | Novel couplers for oxidative hair dyeing | P&G | 2004-02-11 | — | — | CN | disclosed |
| CN-1474681-A | Novel couplers for oxidative hair dyeing | P&G克莱罗尔公司 | 2004-02-11 | — | — | CN | disclosed |
| CN-1474680-A | Novel couplers for oxidative hair dyeing | P&G克莱罗尔公司 | 2004-02-11 | — | — | CN | disclosed |
| CN-1449276-A | Primary intermediates for oxidative dyeing of hair | P & G CLAIROL INC (US) | 2003-10-15 | — | — | CN | disclosed |
| CN-1396819-A | Novel couplers for oxidative hair dyeing | P & G CLAROR INC (US) | 2003-02-12 | — | — | CN | disclosed |
| US-20020166180-A1 | 2-hydroxy-5-amino-biphenyl-derivatives and oxidative hair colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220347187-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | CDK4, CDK6, CDK8 | NISCH 1407/4885GAA 2341/4885NPSR1 4775/4885 |
| US-11230542-B2 | Inhibitors of integrated stress response pathway | ATF4, DDIT3, ATF1 | NISCH 4069/4885GAA 2589/4885NPSR1 1399/4885 |
| US-20230047589-A1 | INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY | ATF4, DDIT3, ATF1 | NISCH 4069/4885GAA 2589/4885NPSR1 1399/4885 |
| US-20020166180-A1 | 2-hydroxy-5-amino-biphenyl-derivatives and oxidative hair colouring agents containing said compounds | AHR, KRT18, HMOX2 | NISCH 1606/4885GAA 4440/4885NPSR1 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.