Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | HPGD | P15428 | 9/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637379 | 0.77 | ALDH1A1 (0.61) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL555863 | 0.76 | MAPK1 (0.70) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL5455541 | 0.74 | ALDH1A1 (0.60) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL3002051 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL27582841 | 0.70 | MEN1 (0.64) | ALDH1A1TSHRMAPK1ALOX15POLB | |
| SCHEMBL555551 | 0.70 | DPP4 (0.54) | ALDH1A1TSHRMAPK1ALOX15MEN1 | |
| SCHEMBL5719404 | 0.70 | DPP4 (0.71) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL8952374 | 0.68 | ALDH1A1 (0.49) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL8952238 | 0.68 | ALDH1A1 (0.49) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL21703516 | 0.67 | ALDH1A1 (0.71) | ALDH1A1HPGDTSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778689-A1 | SUBSTITUTED 8-AMINOALKYLTHIO-XANTHINES, AND THE USE THEREOF AS INHIBITORS OF THE DIPEPTIDYL PEPTIDASE IV | Sanofi-Aventis Deutschland GmbH (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006015691-A1 | SUBSTITUTED 8-AMINOALKYLTHIO-XANTHINES, AND THE USE THEREOF AS INHIBITORS OF THE DIPEPTIDYL PEPTIDASE IV | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-02-16 | — | — | WO | disclosed |