Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | RGS12 | O14924 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391439 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL25566099 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL25455699 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL4267612 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| Hydrochloric Acid SCHEMBL5172733 | 0.98 | KMT2A (0.63) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL13990579 | 0.85 | CYP2D6 (0.58) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL22461952 | 0.85 | CYP2D6 (0.58) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL19647113 | 0.84 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL25833835 | 0.84 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL30367068 | 0.82 | LMNA (0.47) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1273665-B1 | PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS | DAIICHI FINE CHEM CO LTD (JP) | 2007-05-16 | — | — | EP | disclosed |
| US-6835559-B2 | Process for the production of optically active β-amino alcohols | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2004-12-28 | — | — | US | disclosed |
| US-20040091981-A1 | Process for the production of optically active beta-amino alcohols | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1273665-A1 | PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS | Daiichi Fine Chemical Co., Ltd. (JP) | 2003-01-08 | — | — | EP | disclosed |