Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | RGS12 | O14924 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19647113 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL7063882 | 0.85 | CYP2D6 (0.58) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL6058534 | 0.85 | CYP2D6 (0.58) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL25566099 | 0.84 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL4267612 | 0.84 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL25455699 | 0.84 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL5391439 | 0.84 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL5172170 | 0.84 | CYP2D6 (0.62) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| Hydrochloric Acid SCHEMBL5172733 | 0.82 | KMT2A (0.63) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C | |
| SCHEMBL22461952 | 0.81 | CYP2D6 (0.58) | CYP2D6CYP2C19CYP3A4CYP2C9ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701427-B2 | Diels-alder conjugation methods | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701427-B2 | Diels-alder conjugation methods | GLUL, TGM2, GLS | CYP2D6 1514/4885CYP2C19 2963/4885CYP3A4 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.