⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517339 | 1.00 | — | — | |
| SCHEMBL819207 | 1.00 | — | — | |
| SCHEMBL517338 | 1.00 | — | — | |
| SCHEMBL1525454 | 0.97 | ALOX15 (0.74) | — | |
| SCHEMBL29394097 | 0.97 | ALOX15 (0.74) | — | |
| SCHEMBL1374556 | 0.97 | ALOX15 (0.74) | — | |
| SCHEMBL8089487 | 0.97 | ALOX15 (0.74) | — | |
| Diethylamine SCHEMBL1524932 | 0.88 | ALOX15 (1.00) | — | |
| Diethylamine SCHEMBL1524933 | 0.88 | ALOX15 (1.00) | — | |
| Diethylamine SCHEMBL447262 | 0.88 | ALOX15 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180036314-A1 | METHODS AND COMPOSITIONS FOR TREATING PERIPHERAL VASCULAR DISEASE | EXODOS LIFE SCIENCES LP (US) | 2018-02-08 | — | — | US | claimed |
| US-20130053393-A1 | METHODS AND COMPOSITIONS FOR TREATING PERIPHERAL VASCULAR DISEASE | EXODOS LIFE SCIENCES LIMITED PARTNERSHIP (US) | 2013-02-28 | — | — | US | claimed |
| EP-2512479-A1 | METHODS AND COMPOSITIONS FOR TREATING PERIPHERAL VASCULAR DISEASE | Exodos Life Sciences Limited Partnership (US) | 2012-10-24 | — | — | EP | claimed |
| WO-2011075655-A1 | METHODS AND COMPOSITIONS FOR TREATING PERIPHERAL VASCULAR DISEASE | EXODOS LIFE SCIENCES LIMITED PARTNERSHIP (US) | 2011-06-23 | — | — | WO | claimed |
| US-20090326017-A1 | PAIN-RELIEVING COMPOSITIONS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-12-31 | — | — | US | claimed |
| WO-2008098192-A2 | COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY | MAIBACH TODD (US) | 2008-08-14 | — | — | WO | claimed |
| US-20080193385-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY | MAIBACH TODD | 2008-08-14 | — | — | US | claimed |
| WO-2008080194-A1 | PAIN-RELIEVING COMPOSITIONS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-07-10 | — | — | WO | claimed |
| WO-2007100910-A2 | TRANSDERMAL PATCHES CONTAINING A NITRIC OXIDE-DONOR AND A SECOND ACTIVE AGENT AND ASSOCIATED METHODS | CURE THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070202155-A1 | Low dose no donor-containing transdermal patch | CURE THERAPEUTICS, INC. | 2007-08-30 | — | — | US | claimed |
| WO-2007092284-A2 | LOW DOSE NO DONOR-CONTAINING TRANSDERMAL PATCH | CURE THERAPEUCTICS, INC. (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070059351-A1 | Transdermal patches containing a nitric oxide-donor and a second active agent and associated methods | CURE THERAPEUTICS, INC. | 2007-03-15 | — | — | US | claimed |
| US-20030215528-A1 | Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype | QUEENS UNIVERSITY AT KINGSTON (CA) | 2003-11-20 | — | — | US | claimed |
| US-6586478-B2 | Administering nitrogen oxide mimetic | CELLEGY CANADA (CA) | 2003-07-01 | — | — | US | claimed |
| WO-2024006841-A2 | COMPOSITIONS FOR WEIGHT LOSS AND CANCER TREATMENT | KNOWLEDGE PHARMACEUTICALS INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| US-20230346777-A1 | USE OF SGC ACTIVATORS FOR THE TREATMENT OF OPHTHALMOLOGIC DISEASES | BAYER AG (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20220296584-A1 | Membrane Active Molecules | KNOWLEDGE PHARMACEUTICALS INC. | 2022-09-22 | — | — | US | disclosed |
| US-20020102744-A1 | Monitoring nitrosylation of polypeptide substrates; obtain sample, incubate with alkylthiolating agent, reduce nitrosothiol bonds on subatrate, incubate with tag, detect signal | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-08-01 | — | — | US | disclosed |
| WO-2002039119-A2 | METHOD FOR ASSAYING PROTEIN NITROSYLATION | THE JOHNS HOPKINS UNIVERSITY (US) | 2002-05-16 | — | — | WO | disclosed |
| US-20020015740-A1 | Methods and compositions for improving sleep | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2002-02-07 | — | — | US | disclosed |