Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525454 | 1.00 | ALOX15 (0.74) | ALOX15CYP3A4KDM4EMEN1TSHR | |
| SCHEMBL1374556 | 1.00 | ALOX15 (0.74) | ALOX15CYP3A4KDM4EMEN1TSHR | |
| SCHEMBL819207 | 0.97 | — | — | |
| SCHEMBL517338 | 0.97 | — | — | |
| SCHEMBL517340 | 0.97 | — | — | |
| SCHEMBL517339 | 0.97 | — | — | |
| SCHEMBL29394097 | 0.94 | ALOX15 (0.74) | ALOX15CYP3A4KDM4EMEN1TSHR | |
| Diethylamine SCHEMBL1524932 | 0.85 | ALOX15 (1.00) | ALOX15CYP3A4KDM4EMEN1TSHR | |
| Diethylamine SCHEMBL447262 | 0.85 | ALOX15 (1.00) | ALOX15CYP3A4KDM4EMEN1TSHR | |
| Diethylamine SCHEMBL1524933 | 0.85 | ALOX15 (1.00) | ALOX15CYP3A4KDM4EMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700378-B1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | UNIV CALIFORNIA (US) | 2000-12-20 | — | — | EP | disclosed |
| EP-0700378-A1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-03-13 | — | — | EP | disclosed |
| EP-0700378-A4 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | UNIV CALIFORNIA (US) | 1996-01-22 | — | — | EP | disclosed |
| US-5374710-A | Compounds which release nitric oxide upon illumination | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-20 | — | — | US | disclosed |
| WO-1994027957-A1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-08 | — | — | WO | disclosed |