SCHEMBL517356

SCHEMBL517356

CC(C)C(C)c1nc2[nH]c(=O)[nH]c(=O)c2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
ADORA2B P29275 2/20 0.42
GDA Q9Y2T3 3/20 0.38
ACHE P22303 1/20 0.38
XDH P47989 3/20 0.37
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 3/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
ENPP1 P22413 1/20 0.33
RPS6KA3 P51812 1/20 0.33
KDM4E B2RXH2 2/20 0.32
CYP1A2 P05177 2/20 0.32
GAA P10253 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
BLM P54132 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
PABPC1 P11940 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30604637 0.85 MAPT (0.48) MAPTADORA2BGDAACHEXDH
SCHEMBL6033608 0.78 MAPT (0.42) MAPTADORA2BGDAACHEXDH
SCHEMBL18991419 0.76 ADORA2B (0.44) MAPTADORA2BGDAACHEXDH
SCHEMBL7801075 0.72 MAPT (0.43) MAPTADORA2BGDAACHEXDH
SCHEMBL9430257 0.72 PDE3B (0.39) MAPTADORA2BGDAACHEXDH
SCHEMBL9430289 0.71 XDH (0.41) MAPTADORA2BGDAACHEXDH
SCHEMBL9430582 0.71 XDH (0.41) MAPTADORA2BGDAACHEXDH
SCHEMBL1992130 0.71 MAPT (0.42) MAPTADORA2BGDAACHEXDH
SCHEMBL2143500 0.71 MAPT (0.46) MAPTADORA2BGDAACHEXDH
SCHEMBL10997 0.71 MAPT (0.53) MAPTADORA2BGDAACHEXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1912109-B Structural method and application of tissue engineering adipose tissue INST TRANSFUSION MEDICINE ACADEMY MILITARY MEDICAL SCIENCES 2010-09-15 CN claimed
CN-1912109-A Structural method and application of tissue engineering adipose tissue FEILD BLOOD TRANSFUSION INST A (CN) 2007-02-14 CN claimed
CN-1912110-A Method and application of induced differentiating fat originate stem cells to adipocyte FEILD FLOOD TRANSFUSION INST A (CN) 2007-02-14 CN claimed
US-20210284964-A1 HUMAN ADIPOSE TISSUE WHITE AND `BROWN-ON-WHITE` PROGENITORS FOR RECONSTRUCTIVE AND METABOLIC THERAPIES UNIVERSITY OF MASSACHUSETTS 2021-09-16 US disclosed
US-10927348-B2 Human adipose tissue white and ‘brown-on-white’ progenitors for reconstructive and metabolic therapies UNIVERSITY OF MASSACHUSETTS (US) 2021-02-23 US disclosed
US-20180355320-A1 HUMAN ADIPOSE TISSUE WHITE AND `BROWN-ON-WHITE` PROGENITORS FOR RECONSTRUCTIVE AND METABOLIC THERAPIES UNIVERSITY OF MASSACHUSETTS 2018-12-13 US disclosed
US-10093902-B2 Human adipose tissue white and ‘brown-on-white’ progenitors for reconstructive and metabolic therapies UNIVERSITY OF MASSACHUSETTS (US) 2018-10-09 US disclosed
US-20170335288-A1 METHOD OF CLASSIFYING MESENCHYMAL STEM CELLS BY CONTROLLING CELL ADHESION, AND PROTEIN-COATED CULTURE CONTAINER THEREFOR KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-11-23 US disclosed
CN-105779385-A Mesenchymal stem cell culture kit 谷超 2016-07-20 CN disclosed
CN-105734012-A Culture kit for maintaining totipotency of mesenchymal stem cells 赵玲玲 2016-07-06 CN disclosed
US-20160186131-A1 THREE DIMENSIONAL PURIFIED COLLAGEN MATRICES PURDUE RESEARCH FOUNDATION 2016-06-30 US disclosed
US-6852546-B1 Diagnosis of autoimmune disease DIAGNOSTIC HYBRIDS, INC. (US) 2005-02-08 US disclosed
CN-1558897-A oral antidiabetic agent ����-�����ع�˾ 2004-12-29 CN disclosed
CN-1176674-C Rehmannia root extract and its preparing process and application 复旦大学 2004-11-24 CN disclosed
EP-1268846-A4 DIAGNOSIS OF AUTOIMMUNE DISEASE DIAGNOSTIC HYBRIDS INC (US) 2003-06-25 EP disclosed
CN-1400018-A Medicine for curing adiposis, diabetes and related diseases SHEN AIFU (CN) 2003-03-05 CN disclosed
EP-1268846-A1 DIAGNOSIS OF AUTOIMMUNE DISEASE DIAGNOSTIC HYBRIDS, INC. (US) 2003-01-02 EP disclosed
CN-1352696-A Adipose-derived stem cells and grids UNIV PITTSBURGH (US) 2002-06-05 CN disclosed
CN-1317337-A Rehmannia root extract and its preparing process and application UNIV FUDAN (CN) 2001-10-17 CN disclosed
WO-2001075146-A1 DIAGNOSIS OF AUTOIMMUNE DISEASE DIAGNOSTIC HYBRIDS, INC. (US) 2001-10-11 WO disclosed