Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254882 | 0.84 | HSD17B10 (0.50) | ALDH1A1CYP3A4HSD17B10LMNATDP1 | |
| SCHEMBL7246163 | 0.83 | CYP2A6 (0.46) | ALDH1A1CYP3A4CYP2A6CSNK2A1HSD17B10 | |
| SCHEMBL30060011 | 0.82 | CYP2A6 (0.57) | ALDH1A1CYP2A6CSNK2A1HSD17B10LMNA | |
| SCHEMBL6573889 | 0.80 | THRB (0.56) | ALDH1A1CYP3A4CYP2A6CSNK2A1HSD17B10 | |
| SCHEMBL4687459 | 0.80 | CYP2A6 (0.43) | ALDH1A1CYP2A6CSNK2A1HSD17B10KDM4E | |
| SCHEMBL1596044 | 0.79 | CYP2A6 (0.42) | ALDH1A1CYP2A6CSNK2A1HSD17B10KDM4E | |
| SCHEMBL3923680 | 0.78 | HSD17B10 (0.50) | ALDH1A1CYP3A4HSD17B10KDM4ELMNA | |
| SCHEMBL16014529 | 0.77 | CSNK2A1 (0.58) | ALDH1A1CYP3A4CYP2A6CSNK2A1HSD17B10 | |
| SCHEMBL13365533 | 0.77 | CYP2A6 (0.54) | ALDH1A1CYP3A4CYP2A6CSNK2A1HSD17B10 | |
| SCHEMBL31374861 | 0.77 | CYP2A6 (0.54) | ALDH1A1CYP3A4CYP2A6CSNK2A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781240-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006026487-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |