Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871472 | 0.86 | PTGS2 (0.42) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL22616582 | 0.85 | TAAR1 (0.47) | ALDH1A1KDM4EMEN1KMT2AMAP4K4 | |
| SCHEMBL4787759 | 0.85 | AHR (0.42) | HSD17B10SMN1; SMN2MEN1KMT2AMAP4K4 | |
| SCHEMBL3651531 | 0.81 | PLA2G7 (0.44) | CYP2A6ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL30579808 | 0.80 | CYP2A6 (0.46) | CYP2A6CSNK2A1METAP2ALDH1A1HPGD | |
| SCHEMBL7246163 | 0.80 | CYP2A6 (0.46) | CYP2A6CSNK2A1ALDH1A1HSD17B10HPGD | |
| SCHEMBL5174258 | 0.80 | ALDH1A1 (0.52) | CYP2A6CSNK2A1ALDH1A1HSD17B10HPGD | |
| SCHEMBL28106449 | 0.80 | METAP2 (0.42) | METAP2ALDH1A1HSD17B10HPGDSMARCA2 | |
| SCHEMBL19857180 | 0.77 | METAP2 (0.40) | CYP2A6METAP2ALDH1A1HSD17B10HPGD | |
| SCHEMBL29972900 | 0.76 | GRM2 (0.42) | CYP2A6CSNK2A1MAP4K4GRM2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072393-B | 3-Amino-4H-benzo [ E ] [1,2,4] thiadiazine 1, 1-dioxide derivatives as MRGX2 inhibitors | 索伦特治疗有限责任公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-1965642-A2 | PYRAZOLYL CARBOXAMIDES | Bayer CropScience AG (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007068370-A2 | PYRAZOLYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2007-06-21 | — | — | WO | disclosed |