Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1373101 | 0.98 | NPSR1 (0.69) | NPSR1THRBHTR1AKDM4ECYP3A4 | |
| SCHEMBL10403767 | 0.88 | THRB (0.67) | NPSR1THRBHTR1AKDM4EHSD17B10 | |
| SCHEMBL10772825 | 0.86 | THRB (0.65) | NPSR1THRBHTR1AKDM4EHSD17B10 | |
| SCHEMBL5544596 | 0.86 | THRB (0.65) | NPSR1THRBHTR1AKDM4EALDH1A1 | |
| SCHEMBL4405017 | 0.86 | THRB (0.65) | NPSR1THRBHTR1AKDM4EHSD17B10 | |
| SCHEMBL5009465 | 0.85 | HTR1A (0.78) | NPSR1THRBHTR1AKDM4ECYP3A4 | |
| SCHEMBL6360940 | 0.84 | THRB (0.63) | NPSR1THRBHTR1AKDM4EALDH1A1 | |
| SCHEMBL4008925 | 0.83 | THRB (1.00) | NPSR1THRBKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9080030 | 0.82 | HTR1A (0.61) | NPSR1THRBHTR1AKDM4ECYP3A4 | |
| SCHEMBL4010416 | 0.81 | POLB (0.84) | NPSR1THRBKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238974-B1 | HETEROCYCLE DERIVATIVES AND DRUGS | NIPPON SHINYAKU CO LTD (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-6787546-B2 | POTENT ANTICANCER ACTIVITY; WATER SOLUBLE; INJECTION 4-(2-(2-(N-(4-METHOXYBENZENESULFONYL)-N -PIPERIDINOACETYLAMINO)PHENYL)ETHENYL)PYRIDINE 1-OXIDE HYDROCHLORIDE | NIPPON SHINYAKU CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| US-20030022884-A1 | Heterocycle derivatives and drugs | NIPPON SHINYAKU CO., LTD. (JP) | 2003-01-30 | — | — | US | disclosed |
| EP-1238974-A1 | HETEROCYCLE DERIVATIVES AND DRUGS | Nippon Shinyaku Co., Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022884-A1 | Heterocycle derivatives and drugs | ABCC5, CYP3A5, CYP2D6 | NPSR1 153/4885THRB 2921/4885HTR1A 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.