SCHEMBL5174604

SCHEMBL5174604

C/C(=C\C(N)=O)C(=O)NCCO

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.39
ALDH1A1 P00352 4/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CNR1 P21554 2/20 0.32
GAA P10253 1/20 0.31
KDM4E B2RXH2 2/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5174609 0.82 ALDH1A1 (0.45) APEX1ALDH1A1MEN1USP2MAPT
SCHEMBL23030245 0.79 SMN1; SMN2 (0.43) ALDH1A1MEN1KMT2APOLBNPC1
SCHEMBL5176262 0.79 POLB (0.35) ALDH1A1KMT2APOLB
SCHEMBL5176267 0.79 POLB (0.35) ALDH1A1KMT2APOLB
SCHEMBL28252991 0.79 APEX1 (0.43) APEX1ALDH1A1MEN1USP2MAPT
SCHEMBL26009039 0.78 APEX1 (0.38) APEX1ALDH1A1MEN1USP2MAPT
SCHEMBL11375806 0.77 APEX1 (0.42) APEX1ALDH1A1MEN1USP2MAPT
SCHEMBL2745966 0.72 ALDH1A1 (0.38) APEX1ALDH1A1MEN1USP2MAPT
SCHEMBL7930854 0.72 ALDH1A1 (0.59) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL5176643 0.72 POLB (0.34) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6824946-B2 SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
EP-1031414-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-06-16 EP disclosed
US-20040086799-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-05-06 US disclosed
US-6680161-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-01-20 US disclosed
EP-1371500-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-12-17 EP disclosed
US-20030190553-A1 Support with hydrophilic surface; multilayer; latex layer and ink receiver FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed