SCHEMBL5174609

SCHEMBL5174609

CC(=CC(=O)O)C(=O)NCCO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.45
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 4/20 0.35
CYP2C19 P33261 2/20 0.35
CYP1A2 P05177 1/20 0.35
PARP1 P09874 1/20 0.34
CYP2C9 P11712 1/20 0.34
CNR1 P21554 1/20 0.33
TSHR P16473 2/20 0.32
GAA P10253 2/20 0.32
CYP3A4 P08684 1/20 0.32
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5174604 0.82 APEX1 (0.39) ALDH1A1APEX1NPC1RAB9ASMN1; SMN2
SCHEMBL14464554 0.82 PLA2G2A (0.44) ALDH1A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL18504333 0.80 ALDH1A1 (0.49) ALDH1A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL28252991 0.80 APEX1 (0.43) ALDH1A1APEX1NPC1RAB9ASMN1; SMN2
SCHEMBL26009039 0.80 APEX1 (0.38) ALDH1A1APEX1NPC1RAB9ASMN1; SMN2
SCHEMBL21647243 0.78 ALDH1A1 (0.38) ALDH1A1MEN1USP2MAPTKMT2A
SCHEMBL17858888 0.78 ALDH1A1 (0.38) ALDH1A1MEN1USP2MAPTKMT2A
SCHEMBL5176269 0.78 ALDH1A1 (0.47) ALDH1A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL11375806 0.78 APEX1 (0.42) ALDH1A1APEX1NPC1RAB9ASMN1; SMN2
SCHEMBL18503929 0.77 ALDH1A1 (0.46) ALDH1A1APEX1HTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6824946-B2 SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
EP-1031414-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-06-16 EP disclosed
US-20040086799-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-05-06 US disclosed
US-6680161-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-01-20 US disclosed
EP-1371500-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-12-17 EP disclosed
US-20030190553-A1 Support with hydrophilic surface; multilayer; latex layer and ink receiver FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed