SCHEMBL5174649

SCHEMBL5174649

CN(C)c1ccc(N=Nc2ncc[nH]2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.54
RAB9A P51151 8/20 0.54
KMT2A Q03164 8/20 0.54
MEN1 O00255 6/20 0.54
HSP90AA1 P07900 1/20 0.54
AGTR1 P30556 1/20 0.54
MAOA P21397 2/20 0.53
MAOB P27338 2/20 0.53
MAPK1 P28482 5/20 0.52
ALDH1A1 P00352 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
TSHR P16473 4/20 0.52
HSD17B10 Q99714 3/20 0.52
MAPT P10636 4/20 0.45
POLB P06746 2/20 0.45
KDM4E B2RXH2 2/20 0.45
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
NSD2 O96028 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18087701 1.00 NPC1 (0.54) NPC1RAB9AKMT2AMEN1HSP90AA1
Hydrochloric Acid SCHEMBL5711645 0.98 NPC1 (0.53) NPC1RAB9AKMT2AMEN1HSP90AA1
SCHEMBL13485172 0.85 MAPK1 (0.44) NPC1RAB9AKMT2AMEN1HSP90AA1
SCHEMBL14088378 0.84 NPC1 (0.49) NPC1RAB9AKMT2AMEN1HSP90AA1
SCHEMBL13201267 0.80 NPC1 (0.58) NPC1RAB9AKMT2AMEN1HSP90AA1
SCHEMBL5822637 0.78 KMT2A (0.44) NPC1RAB9AKMT2AMEN1HSP90AA1
SCHEMBL1405466 0.77 ALDH1A1 (0.81) NPC1RAB9AKMT2AMEN1MAOA
SCHEMBL3217840 0.77 ALDH1A1 (0.81) NPC1RAB9AKMT2AMEN1MAOA
SCHEMBL3217836 0.77 ALDH1A1 (0.81) NPC1RAB9AKMT2AMEN1MAOA
SCHEMBL3217829 0.77 ALDH1A1 (0.81) NPC1RAB9AKMT2AMEN1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3271423-A1 CATIONIC DIRECT DYES BASF SE (DE) 2018-01-24 EP disclosed
WO-2016146813-A1 CATIONIC DIRECT DYES BASF SE (DE) 2016-09-22 WO disclosed
EP-1781379-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2007-05-09 EP disclosed
EP-1737417-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2007-01-03 EP disclosed
EP-1735059-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2006-12-27 EP disclosed
EP-1715840-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2006-11-02 EP disclosed
WO-2006026495-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2006-03-09 WO disclosed
WO-2005099656-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-10-27 WO disclosed
WO-2005077324-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-08-25 WO disclosed
WO-2005074875-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-08-18 WO disclosed