Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933089 | 0.81 | MEN1 (0.58) | NPC1RAB9AKMT2AMEN1HSP90AA1 | |
| SCHEMBL18066434 | 0.81 | MEN1 (0.58) | NPC1RAB9AKMT2AMEN1HSP90AA1 | |
| SCHEMBL14606324 | 0.81 | MEN1 (0.58) | NPC1RAB9AKMT2AMEN1HSP90AA1 | |
| SCHEMBL11609544 | 0.81 | MEN1 (0.58) | NPC1RAB9AKMT2AMEN1HSP90AA1 | |
| SCHEMBL6933093 | 0.81 | MEN1 (0.58) | NPC1RAB9AKMT2AMEN1HSP90AA1 | |
| SCHEMBL11609547 | 0.81 | MEN1 (0.58) | NPC1RAB9AKMT2AMEN1HSP90AA1 | |
| SCHEMBL5174649 | 0.80 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1HSP90AA1 | |
| SCHEMBL3168850 | 0.80 | RAB9A (0.54) | NPC1RAB9AKMT2AMEN1HSP90AA1 | |
| SCHEMBL3168842 | 0.80 | RAB9A (0.54) | NPC1RAB9AKMT2AMEN1HSP90AA1 | |
| SCHEMBL18087701 | 0.80 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7771490-B2 | Dyes containing a thiol group | CIBA CORPORATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20090300857-A1 | hair dyes; washfast; thioethylation | CIBA CORPORATION (US) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090300857-A1 | hair dyes; washfast; thioethylation | TMT1A, WASHC4, TPH1 | NPC1 3841/4885RAB9A 3435/4885KMT2A 1436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.