Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.52 |
| ▸ | ITGAV | P06756 | 5/20 | 0.52 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588059 | 0.96 | ITGB3 (0.47) | ITGB3ITGA2BITGAVYAP1HDAC8 | |
| SCHEMBL4918524 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BITGAVLMNA | |
| SCHEMBL4835350 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BITGAVLMNA | |
| SCHEMBL7218511 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BITGAVEPHX2 | |
| SCHEMBL14253147 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BITGAV | |
| SCHEMBL4832543 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BITGAVLMNA | |
| SCHEMBL5560208 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BITGAV | |
| SCHEMBL7216246 | 0.81 | ITGB3 (0.64) | ITGB3ITGA2BITGAV | |
| SCHEMBL7224008 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL5177244 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BITGAVHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820991-B1 | Cycloalkyl derivatives as bone resorption inhibitors and vitronectin receptor antagonists | HOECHST AG (DE) | 2007-08-29 | — | — | EP | disclosed |
| EP-0820991-A2 | Cycloalkyl derivatives as bone resorption inhibitors and vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-28 | — | — | EP | disclosed |