Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.64 |
| ▸ | ITGAV | P06756 | 18/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.64 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218511 | 0.91 | ITGB3 (0.55) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL4835350 | 0.89 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL4918524 | 0.89 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL7138885 | 0.85 | ITGB3 (0.76) | ITGB3ITGAVITGA2B | |
| SCHEMBL3368836 | 0.85 | ITGB3 (0.76) | ITGB3ITGAVITGA2B | |
| SCHEMBL7217041 | 0.85 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7216195 | 0.85 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL4832543 | 0.84 | ITGB3 (0.55) | ITGB3ITGAVITGA2B | |
| SCHEMBL14253147 | 0.84 | ITGB3 (0.52) | ITGB3ITGAVITGA2B | |
| SCHEMBL5174657 | 0.81 | ITGB3 (0.52) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602878-B1 | Acylquanidine derivatives, method for preparing same, application as medicines and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. (FR) | 2003-08-05 | — | — | US | claimed |
| US-6602878-B1 | Acylquanidine derivatives, method for preparing same, application as medicines and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. (FR) | 2003-08-05 | — | — | US | disclosed |