Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 7/20 | 0.44 |
| ▸ | GCK | P35557 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175169 | 0.78 | RAB9A (0.44) | RAB9ANPC1ALPLALPGPLAA | |
| SCHEMBL5177261 | 0.76 | HDAC4 (0.49) | RAB9ANPC1HDAC4MEF2DALPL | |
| SCHEMBL5175187 | 0.75 | KDM4E (0.52) | RAB9AALPLALPGPLAAKDM4E | |
| SCHEMBL5176316 | 0.75 | SMN1; SMN2 (0.48) | RAB9ANPC1GCKKDM4EMEN1 | |
| SCHEMBL5175721 | 0.74 | ALPL (0.51) | RAB9AALPLALPGPLAAKDM4E | |
| SCHEMBL5174315 | 0.74 | NPSR1 (0.56) | RAB9ANPC1ALPLALPGPLAA | |
| SCHEMBL5176198 | 0.74 | ALPL (0.55) | RAB9ANPC1ALPLALPGPLAA | |
| SCHEMBL16092998 | 0.74 | RAB9A (0.77) | RAB9ANPC1SCDMEN1GAA | |
| SCHEMBL10591917 | 0.73 | RAB9A (0.76) | RAB9ANPC1HDAC4EP300MEF2D | |
| SCHEMBL21232534 | 0.72 | RAB9A (0.60) | RAB9ANPC1HDAC4EP300MEF2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | claimed |
| EP-1746088-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | Wella Aktiengesellschaft (DE) | 2007-01-24 | — | — | EP | claimed |
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | disclosed |
| WO-2007010463-A2 | 2-AMINO-5-AMINOMETHYL-PHENOL DERIVATIVES AND AGENT FOR COLORING KERATIN FIBERS COMPRISING THESE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-01-25 | — | — | WO | disclosed |
| EP-1746088-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | Wella Aktiengesellschaft (DE) | 2007-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | KRT18, ALDH7A1, MKI67 | RAB9A 3911/4885NPC1 4851/4885HDAC4 1354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.