SCHEMBL5175040

SCHEMBL5175040

NS(=O)(=O)c1ccc(NC(=O)/C=C\C(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LPAR2 Q9HBW0 1/20 0.64
▸ LPAR3 Q9UBY5 1/20 0.64
▸ MAPT P10636 6/20 0.62
▸ L3MBTL1 Q9Y468 3/20 0.62
▸ THRB P10828 2/20 0.62
▸ TDP2 O95551 1/20 0.62
▸ GAA P10253 1/20 0.62
▸ CA12 O43570 6/20 0.61
▸ CA1 P00915 6/20 0.61
▸ CA2 P00918 6/20 0.61
▸ CA9 Q16790 6/20 0.61
▸ ALDH1A1 P00352 6/20 0.61
▸ POLB P06746 3/20 0.61
▸ KMT2A Q03164 2/20 0.61
▸ NMT1 P30419 1/20 0.60
▸ KDM4E B2RXH2 4/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.58
▸ RAB9A P51151 2/20 0.58
▸ TDP1 Q9NUW8 1/20 0.58
▸ LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5481896 1.00 LPAR2 (0.64) LPAR2LPAR3MAPTL3MBTL1THRB
SCHEMBL5177092 1.00 LPAR2 (0.64) LPAR2LPAR3MAPTL3MBTL1THRB
SCHEMBL5481885 0.87 MAPT (0.63) MAPTL3MBTL1CA12CA1CA2
SCHEMBL1827416 0.87 MAPT (0.63) MAPTL3MBTL1CA12CA1CA2
SCHEMBL15078372 0.86 ALDH1A1 (0.68) LPAR2LPAR3MAPTL3MBTL1THRB
SCHEMBL22663672 0.86 ALDH1A1 (0.68) LPAR2LPAR3MAPTL3MBTL1THRB
SCHEMBL2016896 0.85 ALDH1A1 (0.67) LPAR2LPAR3MAPTL3MBTL1THRB
SCHEMBL2016892 0.85 ALDH1A1 (0.67) LPAR2LPAR3MAPTL3MBTL1THRB
SCHEMBL8673997 0.85 ALDH1A1 (0.67) LPAR2LPAR3MAPTL3MBTL1THRB
SCHEMBL11133691 0.84 LPAR2 (0.88) LPAR2LPAR3MAPTL3MBTL1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 — — EP disclosed
US-7300964-B2 Carbon black DEGUSSA AG (DE) 2007-11-27 — — US disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 — — EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 — — EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 — — EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 — — US disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 — — EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 — — US disclosed
US-20050031528-A1 Carbon black UBS LIMITED (GB) 2005-02-10 — — US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 — — EP disclosed
EP-1281516-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-02-05 — — EP disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 — — US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 — — US disclosed
US-20020096089-A1 Having organic groups connected by one or two carbon atoms of a C-C single or double bond that are not part of an aromatic system; reacting with maleic anhydride then hydrolyzing to form carboxylic acid groups UBS LIMITED (GB) 2002-07-25 — — US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 — — US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 — — EP disclosed
US-20010032569-A1 Carbon black DEGUSSA AG (DE) 2001-10-25 — — US disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 — — EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 — — EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 — — EP disclosed
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