Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 11/20 | 0.61 |
| ▸ | CA2 | P00918 | 11/20 | 0.61 |
| ▸ | CA12 | O43570 | 10/20 | 0.61 |
| ▸ | CA9 | Q16790 | 10/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827416 | 1.00 | MAPT (0.63) | MAPTALDH1A1DDAH1HTTCA1 | |
| SCHEMBL5175040 | 0.87 | LPAR2 (0.64) | MAPTALDH1A1CA1CA2CA12 | |
| SCHEMBL5177092 | 0.87 | LPAR2 (0.64) | MAPTALDH1A1CA1CA2CA12 | |
| SCHEMBL97458 | 0.87 | ALDH1A1 (0.63) | MAPTALDH1A1DDAH1HTTCA1 | |
| SCHEMBL5481896 | 0.87 | LPAR2 (0.64) | MAPTALDH1A1CA1CA2CA12 | |
| SCHEMBL2016893 | 0.87 | ALDH1A1 (0.63) | MAPTALDH1A1DDAH1HTTCA1 | |
| SCHEMBL2429556 | 0.86 | ALDH1A1 (0.81) | MAPTALDH1A1DDAH1HTTKMT2A | |
| SCHEMBL5176311 | 0.83 | CA12 (0.62) | MAPTALDH1A1CA1CA2CA12 | |
| SCHEMBL19559868 | 0.83 | CA12 (0.62) | MAPTALDH1A1CA1CA2CA12 | |
| SCHEMBL202328 | 0.79 | TGM2 (0.70) | CA1CA2CA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300964-B2 | Carbon black | DEGUSSA AG (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20050031528-A1 | Carbon black | UBS LIMITED (GB) | 2005-02-10 | — | — | US | disclosed |
| US-6660075-B2 | Having organic groups connected by one or two carbon atoms of a C-C single or double bond that are not part of an aromatic system; reacting with maleic anhydride then hydrolyzing to form carboxylic acid groups | DEGUSSA AG (DE) | 2003-12-09 | — | — | US | disclosed |
| US-20020096089-A1 | Having organic groups connected by one or two carbon atoms of a C-C single or double bond that are not part of an aromatic system; reacting with maleic anhydride then hydrolyzing to form carboxylic acid groups | UBS LIMITED (GB) | 2002-07-25 | — | — | US | disclosed |
| US-20010032569-A1 | Carbon black | DEGUSSA AG (DE) | 2001-10-25 | — | — | US | disclosed |