Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.60 |
| ▸ | BCR | P11274 | 6/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.60 |
| ▸ | KIT | P10721 | 3/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | FYN | P06241 | 1/20 | 0.60 |
| ▸ | CSF1R | P07333 | 1/20 | 0.60 |
| ▸ | YES1 | P07947 | 1/20 | 0.60 |
| ▸ | LYN | P07948 | 1/20 | 0.60 |
| ▸ | HCK | P08631 | 1/20 | 0.60 |
| ▸ | FGR | P09769 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | SLC25A6 | P12236 | 1/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | BRAF | P15056 | 1/20 | 0.60 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716325 | 0.88 | ABL1 (0.75) | ABL1BCRPDGFRBKITPDGFRA | |
| SCHEMBL7151895 | 0.87 | ABL1 (0.71) | ABL1BCRPDGFRBKITPDGFRA | |
| SCHEMBL5501640 | 0.86 | ABL1 (0.56) | ABL1BCRPDGFRBKITPDGFRA | |
| SCHEMBL5176115 | 0.86 | ABL1 (0.56) | ABL1BCRPDGFRBKITPDGFRA | |
| SCHEMBL6871374 | 0.86 | ABL1 (0.58) | ABL1BCRPDGFRBKITPDGFRA | |
| SCHEMBL5512481 | 0.82 | ABL1 (0.51) | ABL1BCRPDGFRBKITPDGFRA | |
| SCHEMBL7038373 | 0.82 | ABL1 (0.52) | ABL1BCRPDGFRBKITPDGFRA | |
| SCHEMBL7039197 | 0.82 | ABL1 (0.52) | ABL1BCRPDGFRBKITPDGFRA | |
| SCHEMBL5972230 | 0.81 | ABL1 (0.60) | ABL1BCRPDGFRBKITPDGFRA | |
| SCHEMBL5502625 | 0.81 | ABL1 (0.59) | ABL1BCRPDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746990-A1 | USE OF MAST CELLS INHIBITORS FOR TREATING PATIENTS EXPOSED TO CHEMICAL OR BIOLOGICAL WEAPONS | AB Science (FR) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005112920-A1 | USE OF MAST CELLS INHIBITORS FOR TREATING PATIENTS EXPOSED TO CHEMICAL OR BIOLOGICAL WEAPONS | AB SCIENCE (FR) | 2005-12-01 | — | — | WO | disclosed |