Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.56 |
| ▸ | BCR | P11274 | 7/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871374 | 0.92 | ABL1 (0.58) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL718498 | 0.89 | ABL1 (0.70) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL5175191 | 0.86 | ABL1 (0.60) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL716396 | 0.85 | ABL1 (0.75) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL5512481 | 0.85 | ABL1 (0.51) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL7038373 | 0.84 | ABL1 (0.52) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL717030 | 0.83 | GAA (0.65) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL5972230 | 0.82 | ABL1 (0.60) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL7151895 | 0.82 | ABL1 (0.71) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL14586437 | 0.82 | ABL1 (0.72) | ABL1BCRPDGFRBHDAC3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742633-A2 | USE OF C-KIT INHIBITORS FOR TREATING FIBROSIS | AB Science (FR) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005102346-A2 | USE OF C-KIT INHIBITORS FOR TREATING FIBROSIS | AB SCIENCE (FR) | 2005-11-03 | — | — | WO | disclosed |