Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.51 |
| ▸ | BCR | P11274 | 6/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716720 | 0.92 | ABL1 (0.61) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL7039197 | 0.89 | ABL1 (0.52) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL7038373 | 0.89 | ABL1 (0.52) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL5176115 | 0.85 | ABL1 (0.56) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL6275041 | 0.84 | ABL1 (0.53) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL5175191 | 0.82 | ABL1 (0.60) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL714550 | 0.81 | ABL1 (0.62) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL6871374 | 0.80 | ABL1 (0.58) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL717519 | 0.80 | ABL1 (0.62) | ABL1BCRPDGFRBHDAC3KDR | |
| SCHEMBL5972220 | 0.79 | MEN1 (0.55) | KDM4EALDH1A1PHGDHRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758654-A1 | USE OF C-KIT INHIBITORS FOR TREATING PLASMODIUM RELATED DISEASES | AB Science (FR) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005102455-A1 | USE OF C-KIT INHIBITORS FOR TREATING PLASMODIUM RELATED DISEASES | AB SCIENCE (FR) | 2005-11-03 | — | — | WO | disclosed |