Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5174469 | 0.93 | ITGB3 (0.42) | ITGB3ITGA2BLMNAITGAVPPARG | |
| SCHEMBL4832623 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2BLMNAITGAV | |
| SCHEMBL4894038 | 0.83 | LMNA (0.42) | ITGB3ITGA2BLMNAITGAVPPARG | |
| SCHEMBL7046619 | 0.77 | LMNA (0.48) | ITGB3ITGA2BLMNAITGAV | |
| SCHEMBL4834857 | 0.77 | ITGB3 (0.46) | ITGB3ITGA2BLMNAITGAVITGB1 | |
| SCHEMBL4876032 | 0.76 | ITGB3 (0.45) | ITGB3ITGA2BLMNAITGAV | |
| SCHEMBL4832505 | 0.76 | ITGB3 (0.45) | ITGB3ITGA2BLMNAITGAV | |
| SCHEMBL4894047 | 0.75 | LMNA (0.43) | ITGB3ITGA2BLMNAITGAVITGB1 | |
| SCHEMBL14316415 | 0.74 | ACACB (0.42) | — | |
| SCHEMBL14253141 | 0.73 | ITGB3 (0.41) | ITGB3ITGA2BITGAVITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820991-B1 | Cycloalkyl derivatives as bone resorption inhibitors and vitronectin receptor antagonists | HOECHST AG (DE) | 2007-08-29 | — | — | EP | claimed |