SCHEMBL5175203

SCHEMBL5175203

C[Si](C)(C1=CC=CC1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.37
SLC22A2 O15244 1/20 0.31
SLC22A3 O75751 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052518 0.83 GPR3 (0.32) GPR3
SCHEMBL6678473 0.83 GPR3 (0.32) GPR3
Hydrochloric Acid SCHEMBL7051182 0.81 GPR3 (0.30) GPR3
Hydrochloric Acid SCHEMBL7051978 0.81 GPR3 (0.30) GPR3
Hydrochloric Acid SCHEMBL7052494 0.81 GPR3 (0.30) GPR3
Hydrochloric Acid SCHEMBL7052532 0.81 GPR3 (0.30) GPR3
SCHEMBL6659150 0.79 GPR3 (0.31) GPR3
SCHEMBL1452248 0.78 SLC6A2 (0.31)
SCHEMBL7122451 0.77 GPR3 (0.31) GPR3
SCHEMBL7130043 0.77 NTRK1 (0.33) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1787971-A2 Process for preparing aryl allyl ethers Dow Gloval Technologies Inc. (US) 2007-05-23 EP disclosed
CN-1675155-A Process for preparing aryl allyl ethers DOW GLOBAL TECHNOLOGIES INC (US) 2005-09-28 CN disclosed
EP-1546078-A1 PROCESS FOR PREPARING ARYL ALLYL ETHERS Dow Global Technologies Inc. (US) 2005-06-29 EP disclosed
US-20050033094-A1 Process for preparing aryl allyl ethers BORIACK CLINTON J (US) 2005-02-10 US disclosed
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
EP-1046642-B1 Process for preparation of silyl-bridged fluorenyl-cyclopentadienyl ligands and silyl-bridged fluorenyl-cyclopentadienyl metallocenes BASELL POLYOLEFINE GMBH (DE) 2004-06-30 EP disclosed
EP-1080084-B1 PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS DOW GLOBAL TECHNOLOGIES INC (US) 2004-05-06 EP disclosed
WO-2004013076-A1 PROCESS FOR PREPARING ARYL ALLYL ETHERS DOW GLOBAL TECHNOLOGIES INC. (US) 2004-02-12 WO disclosed
US-20040024263-A1 Process for preparing aryl allyl ethers BORIACK CLINTON J (US) 2004-02-05 US disclosed
EP-0628577-B2 Silyl bridged metallocenes and use thereof PHILLIPS PETROLEUM CO (US) 2002-10-09 EP disclosed
EP-0628577-B1 Silyl bridged metallocenes and use thereof PHILLIPS PETROLEUM CO (US) 1999-03-03 EP disclosed
EP-0875517-A1 Novel homopolymers of propylene exhibiting more than 50% syndiotacticity and more than 50 wt-% xylene solubles PHILLIPS PETROLEUM COMPANY (US) 1998-11-04 EP disclosed
US-5670589-A COORDINATION POLYMERIZATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1997-09-23 US disclosed
US-5627118-A CATALYSTS FOR OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US disclosed
EP-0726271-A1 Organoaluminoxy product, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1996-08-14 EP disclosed
EP-0693497-A2 Process for the preparation of silicon-bridged asymmetric cyclopentadienyl-, indenyl- and fluorenyl-containing ligand systems PCD-Polymere Gesellschaft m.b.H. (AT) 1996-01-24 EP disclosed
US-5459218-A Containing fluorene ring PHILLIPS PETROLEUM COMPANY (US) 1995-10-17 US disclosed
US-5401817-A Syndiotactic polypropylene PHILLIPS PETROLEUM COMPANY (US) 1995-03-28 US disclosed
US-5393911-A Cyclopentadiene type compounds and method for making PHILLIPS PETROLEUM COMPANY (US) 1995-02-28 US disclosed
EP-0628577-A2 Silyl bridged metallocenes and use thereof PHILLIPS PETROLEUM COMPANY (US) 1994-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040024263-A1 Process for preparing aryl allyl ethers PICALM, AP2M1, AP1M1 GPR3 2273/4885SLC22A2 4560/4885SLC22A3 4633/4885
US-20050033094-A1 Process for preparing aryl allyl ethers PICALM, AP2M1, AP1M1 GPR3 2273/4885SLC22A2 4560/4885SLC22A3 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.