SCHEMBL5175437

SCHEMBL5175437

CCCCOC(=O)CCC(N)(CCC(=O)O)CCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.46
HTR2C P28335 1/20 0.45
S1PR1 P21453 2/20 0.45
S1PR3 Q99500 2/20 0.45
S1PR4 O95977 1/20 0.45
PAM P19021 2/20 0.42
NAAA Q02083 1/20 0.42
ALDH1A1 P00352 4/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
THRB P10828 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPK1 P28482 2/20 0.40
AKR1B1 P15121 1/20 0.39
DNM1 Q05193 1/20 0.39
ATM Q13315 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16126196 0.93 DGKA (0.52) DGKAHTR2CPAMNAAAALDH1A1
SCHEMBL15129332 0.91 S1PR1 (0.43) DGKAHTR2CS1PR1S1PR3S1PR4
SCHEMBL15129331 0.84 DGKA (0.43) DGKAHTR2CS1PR1S1PR3S1PR4
SCHEMBL13125515 0.83 DGKA (0.42) DGKAHTR2CNAAAALDH1A1PRSS1
SCHEMBL5172684 0.81 ALDH1A1 (0.42) DGKAHTR2CS1PR1S1PR3S1PR4
SCHEMBL7393464 0.80 DGKA (0.46) DGKAHTR2CS1PR1S1PR3S1PR4
Dibutylsuccinate SCHEMBL28147008 0.80 DGKA (0.57) DGKAHTR2CPAMNAAAALDH1A1
SCHEMBL459010 0.80 DGKA (0.57) DGKAHTR2CPAMNAAAALDH1A1
SCHEMBL18483446 0.80 DGKA (0.42) DGKAHTR2CS1PR1S1PR3S1PR4
SCHEMBL28253752 0.79 DGKA (0.48) DGKAHTR2CNAAAALDH1A1PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070014727-A1 Contrast media for nuclear spin tomography with use of the overhauser effect BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-01-18 US disclosed