Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316739 | 0.89 | ITGB1 (0.42) | LMNAFKBP1AMAPTPOLBPKM | |
| SCHEMBL3318583 | 0.82 | ITGB1 (0.59) | L3MBTL1LMNAMAPTITGB1SMN1; SMN2 | |
| SCHEMBL3313318 | 0.81 | ITGB1 (0.51) | L3MBTL1LMNAMAPTPOLBITGB1 | |
| SCHEMBL4627490 | 0.79 | ITGA4 (0.49) | LMNAMAPTITGB1SMN1; SMN2HCRTR1 | |
| SCHEMBL3319930 | 0.77 | ITGB1 (0.61) | LMNAMAPTPOLBALOX15MAPK1 | |
| SCHEMBL3320849 | 0.77 | ITGB1 (0.56) | L3MBTL1LMNAFKBP1ATP53ALOX15 | |
| SCHEMBL1028112 | 0.75 | ITGB1 (0.55) | LMNAMAPTPOLBALOX15MAPK1 | |
| SCHEMBL1030228 | 0.75 | ITGB1 (0.49) | LMNAMAPTPOLBALOX15MAPK1 | |
| SCHEMBL3314608 | 0.75 | ITGB1 (0.46) | GAAMAPTITGB1ITGAVITGA4 | |
| SCHEMBL5173393 | 0.75 | ITGB1 (0.44) | L3MBTL1LMNAGAAMAPTITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870402-A1 | 2,6-quinolinyl and 2,6-naphthyl derivatives, processes for preparing them and their uses as VLA-4 inhibitors | UCB Pharma, S.A. (BE) | 2007-12-26 | — | — | EP | disclosed |