SCHEMBL5175677

SCHEMBL5175677

CCO[SiH](CCCNC(=O)O)OCC

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ACHE P22303 7/20 0.33
EPHX1 P07099 4/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432323 0.83 CA12 (0.34) CA12CA1CA2CA9MEN1
SCHEMBL3476352 0.83 EPHX1 (0.53) CA12CA1CA2CA9ACHE
SCHEMBL483443 0.78 CA12 (0.37) CA12CA1CA2CA9MEN1
SCHEMBL1079018 0.78 APEX1 (0.38) MEN1KMT2AALDH1A1
SCHEMBL11905227 0.77 LTA4H (0.36) MEN1KMT2AALDH1A1
SCHEMBL975253 0.74 CYP2C19 (0.38) MEN1KMT2AALDH1A1
SCHEMBL25389786 0.74 KDM4E (0.34) CA12CA1CA2CA9MEN1
SCHEMBL16592762 0.74 AKR1B1 (0.44) MEN1KMT2AALDH1A1
SCHEMBL25388566 0.73 KDM4E (0.37) CA12CA1CA2CA9MEN1
SCHEMBL25386379 0.73 KDM4E (0.37) CA12CA1CA2CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1869058-A2 PROCESS FOR MAKING SILYLISOCYANURATE General Electric Company (US) 2007-12-26 EP disclosed
WO-2006113182-A2 PROCESS FOR MAKING SILYLISOCYANURATE GENERAL ELECTRIC COMPANY (US) 2006-10-26 WO disclosed