Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175677 | 0.78 | EGLN1 (0.36) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL21610956 | 0.76 | APEX1 (0.49) | APEX1SMN1; SMN2ALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL432323 | 0.76 | CA12 (0.34) | KMT2AMEN1 | |
| SCHEMBL3476352 | 0.76 | EPHX1 (0.53) | — | |
| SCHEMBL1081176 | 0.75 | APEX1 (0.39) | APEX1SMN1; SMN2ALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL3701815 | 0.75 | ZDHHC20 (0.52) | APEX1ALDH1A1ZDHHC20ZDHHC2EGFR | |
| SCHEMBL3701812 | 0.75 | ZDHHC20 (0.52) | APEX1ALDH1A1ZDHHC20ZDHHC2EGFR | |
| SCHEMBL7943779 | 0.75 | TRPA1 (0.34) | — | |
| SCHEMBL22187118 | 0.74 | APEX1 (0.51) | APEX1SMN1; SMN2ALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL7532607 | 0.73 | ZDHHC20 (0.60) | APEX1ZDHHC20ZDHHC2EGFRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981961-B2 | Colloidal aqueous organopolysiloxane dispersions which contain binders and the use thereof | WACKER CHEMIE AG (DE) | 2011-07-19 | — | — | US | disclosed |
| US-20110009553-A1 | COLLOIDAL AQUEOUS ORGANOPOLYSILOXANE DISPERSIONS WHICH CONTAIN BINDERS AND THE USE THEREOF | WACKER CHEMIE AG (DE) | 2011-01-13 | — | — | US | disclosed |
| US-7309746-B2 | Polymers containing silane | WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) | 2007-12-18 | — | — | US | disclosed |
| US-7052773-B2 | Silane-modified polyvinyl alcohol mixtures | WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) | 2006-05-30 | — | — | US | disclosed |
| US-20050182223-A1 | Polymers containing silane | WACKER CHEMIE AG (DE) | 2005-08-18 | — | — | US | disclosed |
| US-20040014857-A1 | Silane-containing polyvinyl alcohol for coating slips | WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) | 2004-01-22 | — | — | US | disclosed |
| US-20040013888-A1 | Silane-modified polyvinyl alcohol mixtures | WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) | 2004-01-22 | — | — | US | disclosed |