Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128361 | 0.78 | KCNA3 (0.57) | MEN1KMT2ACYP2C9MAPTUSP2 | |
| Benzene SCHEMBL5176579 | 0.74 | MAOA (0.54) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL19851151 | 0.74 | MEN1 (0.64) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| Water SCHEMBL27862353 | 0.72 | MEN1 (0.67) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7551854 | 0.72 | CYP1A2 (0.60) | ESR2ESR1MEN1KMT2ACYP2C9 | |
| SCHEMBL2957574 | 0.72 | ALDH1A1 (0.46) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL27450966 | 0.70 | MAOA (0.70) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL21032529 | 0.70 | MAOA (0.52) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL11826766 | 0.69 | KCNA3 (0.42) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL31545095 | 0.69 | MEN1 (0.48) | ESR2ESR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055005-B1 | QUANTITATIVE DETERMINATION OF NUCLEIC ACID AMPLIFICATION PRODUCTS | DADE BEHRING INC (US) | 2007-02-28 | — | — | EP | disclosed |
| US-7037654-B2 | Methods and compositions for enhancing detection in determinations employing cleavable electrophoretic tag reagents | ACLARA BIOSCIENCES, INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040096825-A1 | METHODS AND COMPOSITIONS FOR ENHANCING DETECTION IN DETERMINATIONS EMPLOYING CLEAVABLE ELECTROPHORETIC TAG REAGENTS | ACLARA BIOSCIENCES, INC. | 2004-05-20 | — | — | US | disclosed |
| US-20030175785-A1 | Quantitative determination of nucleic acid amplification products | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2003-09-18 | — | — | US | disclosed |
| US-6573054-B2 | Providing target polynucleotide, reference polynucleotides, oliognucleotide probes, subjecting to isothermal conditions for amplifying to form non- dissociative termolecular complexes; evaluation | DADE BEHRING INC. | 2003-06-03 | — | — | US | disclosed |
| WO-2003042658-A2 | METHODS AND COMPOSITIONS FOR ENHANCING DETECTION IN DETERMINATIONS EMPLOYING CLEAVABLE ELECTROPHORETIC TAG REAGENTS | ACLARA BIOSCIENCES, INC. (US) | 2003-05-22 | — | — | WO | disclosed |
| US-20020182620-A1 | Quantitative determination of nucleic acid amplification products | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2002-12-05 | — | — | US | disclosed |
| US-6365346-B1 | SENSITIVE, SIMPLE METHOD USING SINGLE REACTION MEDIUM, ISOTHERMAL CONDITIONS, AND THREE OR MORE TYPES OF OLIGONUCLEOTIDE PROBES | DADE BEHRING INC. | 2002-04-02 | — | — | US | disclosed |
| WO-2001090399-A2 | DETECTION OF MUTATIONS AND POLYMORPHISMS IN NUCLEIC ACIDS | DADE BEHRING INC. (US) | 2001-11-29 | — | — | WO | disclosed |
| US-6265220-B1 | NON-IMMUNOCHEMICAL METHOD BY REACTING A COMPOUND COMPRISING CIS-1,4-DIOXO-2-BUTENE MOIETY OR HYDROLYTICALLY DERIVED PRECURSOR WITH HOMOCYSTEINE, THEN DETECTING PRODUCT WITHOUT SEPARATION FROM LIQUID | ULLMAN EDWIN F (US) | 2001-07-24 | — | — | US | disclosed |
| EP-1055005-A1 | QUANTITATIVE DETERMINATION OF NUCLEIC ACID AMPLIFICATION PRODUCTS | DADE BEHRING INC. (US) | 2000-11-29 | — | — | EP | disclosed |
| EP-0988400-A1 | METHODS FOR DETERMINING AMOUNTS OF NUCLEIC ACIDS | DADE BEHRING INC. (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1999042616-A1 | METHODS FOR DETERMINING CONCENTRATIONS OF NUCLEIC ACIDS | DADE BEHRING INC. (US) | 1999-08-26 | — | — | WO | disclosed |
| WO-1999042615-A1 | METHODS FOR DETERMINING AMOUNTS OF NUCLEIC ACIDS | DADE BEHRING INC. (US) | 1999-08-26 | — | — | WO | disclosed |
| WO-1999042618-A1 | QUANTITATIVE DETERMINATION OF NUCLEIC ACID AMPLIFICATION PRODUCTS | DADE BEHRING INC. (US) | 1999-08-26 | — | — | WO | disclosed |