Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 7/20 | 0.53 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.53 |
| ▸ | CHRNG | P07510 | 3/20 | 0.53 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952781 | 0.89 | CHRND (0.55) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL7586744 | 0.89 | CHRND (0.55) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL26179142 | 0.89 | CHRND (0.54) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL5177591 | 0.88 | CTSS (0.53) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL26605054 | 0.88 | CTSS (0.53) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL15839930 | 0.87 | OPRD1 (0.54) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL29630355 | 0.86 | CHRND (0.47) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL30493746 | 0.85 | GRIA1 (0.61) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL29707530 | 0.84 | CHRND (0.47) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL30468670 | 0.84 | CHRND (0.47) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037249-A1 | Molecules that block viral infectivity and methods of use thereof | GOOBAR-LARSSON LAURA | 2007-02-15 | — | — | US | disclosed |
| US-7012129-B2 | Antiviral composition comprising glycine amide | TRIPEP AB (SE) | 2006-03-14 | — | — | US | disclosed |
| EP-1436317-A1 | MOLECULES THAT BLOCK VIRAL INFECTIVITY AND METHODS OF USE THEREOF | TRIPEP AB (SE) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003024995-A1 | MOLECULES THAT BLOCK VIRAL INFECTIVITY AND METHODS OF USE THEREOF | TRIPEP AB (SE) | 2003-03-27 | — | — | WO | disclosed |