Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31432180 | 0.83 | KDM4E (0.66) | KDM4ETAAR1KMT2AAPEX1CYP1A2 | |
| SCHEMBL12172746 | 0.83 | KDM4E (0.66) | KDM4ETAAR1KMT2AAPEX1CYP1A2 | |
| SCHEMBL5690435 | 0.83 | NPC1 (0.65) | CYP1A2HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL20429133 | 0.81 | KDM4E (0.62) | KDM4ETAAR1KMT2AAPEX1CYP1A2 | |
| SCHEMBL5716639 | 0.80 | RAB9A (0.39) | KDM4ETAAR1KMT2AHTTNPC1 | |
| SCHEMBL5716644 | 0.80 | NPC1 (0.39) | KDM4ETAAR1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL5500095 | 0.79 | NPC1 (0.47) | KDM4ETAAR1KMT2AHTTNPC1 | |
| SCHEMBL28356824 | 0.78 | KDM4E (0.73) | KDM4ETAAR1KMT2AAPEX1CYP1A2 | |
| SCHEMBL6446809 | 0.77 | KDM4E (0.51) | KDM4ETAAR1KMT2AAPEX1CYP1A2 | |
| SCHEMBL21185859 | 0.74 | KDM4E (0.57) | KDM4ETAAR1KMT2AAPEX1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789382-A2 | OPTICALLY ACTIVE PHTHALAMIDES | Bayer CropScience AG (DE) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006024412-A2 | OPTICALLY ACTIVE PHTHALAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-03-09 | — | — | WO | disclosed |