Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5716651 | 0.87 | RAB9A (0.38) | RAB9ANPC1KDM4ETAAR1POLB | |
| SCHEMBL5716644 | 0.84 | NPC1 (0.39) | RAB9ANPC1KDM4ETAAR1POLB | |
| SCHEMBL5177997 | 0.84 | NPC1 (0.39) | RAB9ANPC1KDM4ETAAR1POLB | |
| SCHEMBL5716645 | 0.84 | NPC1 (0.51) | RAB9ANPC1KDM4ETAAR1POLB | |
| SCHEMBL5177699 | 0.80 | KDM4E (0.59) | RAB9ANPC1KDM4ETAAR1POLB | |
| SCHEMBL5716646 | 0.78 | KCNA3 (0.40) | RAB9ANPC1KDM4ETAAR1POLB | |
| SCHEMBL551264 | 0.77 | KMT2A (0.44) | RAB9APOLBALDH1A1MAPTKMT2A | |
| SCHEMBL551897 | 0.76 | ALDH1A1 (0.50) | KDM4EPOLBALDH1A1KMT2AF2R | |
| SCHEMBL6227836 | 0.76 | KCNA3 (0.38) | RAB9ANPC1KDM4ETAAR1POLB | |
| SCHEMBL5500095 | 0.75 | NPC1 (0.47) | RAB9ANPC1KDM4ETAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727804-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005095351-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |