Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 14/20 | 0.48 |
| ▸ | ARG2 | P78540 | 12/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ODC1 | P11926 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185635 | 0.95 | ARG1 (0.52) | ARG1ARG2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL14088071 | 0.91 | ARG2 (0.53) | ARG1ARG2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL23010905 | 0.91 | ARG1 (0.48) | ARG1ARG2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL6129347 | 0.91 | ARG2 (0.53) | ARG1ARG2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL11414745 | 0.89 | ARG2 (0.52) | ARG1ARG2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL16887806 | 0.89 | ARG2 (0.52) | ARG1ARG2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL7087301 | 0.88 | ARG2 (0.55) | ARG1ARG2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL11421459 | 0.86 | ARG2 (0.53) | ARG1ARG2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL21219814 | 0.86 | ARG2 (0.53) | ARG1ARG2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL6666220 | 0.86 | ARG2 (0.63) | ARG1ARG2MEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992490-B2 | Flowable formed methionine products and method for producing the same | DEGUSSA (DE) | 2007-08-29 | — | — | EP | claimed |
| EP-0992490-B1 | Flowable formed methionine products and method for producing the same | DEGUSSA (DE) | 2003-05-28 | — | — | EP | claimed |