SCHEMBL51783

SCHEMBL51783

CC(C)c1ccc(CCl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 2/20 0.43
ALDH1A1 P00352 1/20 0.43
PYCR1 P32322 1/20 0.42
RAB9A P51151 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
TYR P14679 2/20 0.41
HTR1D P28221 1/20 0.40
HTR1B P28222 1/20 0.40
NPC1 O15118 1/20 0.40
FAAH O00519 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30702238 0.97 IDO1 (0.50) IDO1SMN1; SMN2HTTALDH1A1PYCR1
SCHEMBL31496031 0.97 IDO1 (0.50) IDO1SMN1; SMN2HTTALDH1A1PYCR1
SCHEMBL11031906 0.97 IDO1 (0.50) IDO1SMN1; SMN2HTTALDH1A1PYCR1
SCHEMBL9502730 0.87 IDO1 (0.47) IDO1SMN1; SMN2HTTALDH1A1RAB9A
Propionic Acid SCHEMBL28460016 0.84 USP5 (0.47) SMN1; SMN2HTTALDH1A1RAB9AMEN1
SCHEMBL10882893 0.82 CYP3A4 (0.43) IDO1SMN1; SMN2ALDH1A1RAB9AMEN1
SCHEMBL4574471 0.82 TSHR (0.41) IDO1SMN1; SMN2HTTALDH1A1L3MBTL1
SCHEMBL5273198 0.81 IDO1 (0.41) IDO1SMN1; SMN2HTTALDH1A1PYCR1
SCHEMBL5063575 0.81 BCHE (0.42) IDO1SMN1; SMN2HTTALDH1A1RAB9A
SCHEMBL24507350 0.80 FAAH (0.36) IDO1SMN1; SMN2HTTALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708044-A Andrographolide derivative containing thiazolidine ketone heterocycle, preparation method and application thereof 西北农林科技大学 2025-03-28 CN claimed
CN-117779469-A Construction method of host and guest of photodynamic/quaternary ammonium salt/boric acid antibacterial composite PET fiber coating 浙江豪欣纺织有限公司 2024-03-29 CN claimed
CN-117777411-A Crosslinked methylene aromatic hydrocarbon high polymer and synthesis method thereof 乐山师范学院 2024-03-29 CN claimed
US-5565602-A REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST PHILLIPS PETROLEUM COMPANY (US) 1996-10-15 US claimed
EP-0116370-B1 METHOD FOR PREPARATION OF 8-METHOXY-4,8-DIMETHYL-1-(4-ISOPROPYLPHENYL)-NONANE STAUFFER CHEMICAL COMPANY (US) 1986-07-23 EP claimed
US-4484007-A Process for preparation of arylterpenoid insect maturation inhibitors SCM CORPORATION (US) 1984-11-20 US claimed
US-4482751-A Method for preparation of 8-methoxy-4,8-dimethyl-1-(4-isopropylphenyl)-nonane STAUFFER CHEMICAL COMPANY (US) 1984-11-13 US claimed
EP-0116370-A1 Method for preparation of 8-methoxy-4,8-dimethyl-1-(4-isopropylphenyl)-nonane STAUFFER CHEMICAL COMPANY (US) 1984-08-22 EP claimed
EP-0034430-B1 PROCESS FOR PREPARING ARYLACETALDEHYDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-05 EP claimed
US-4338467-A IN THE PRESENCE OF A COBALT CATALYST AND A NITRILE SOLVENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-06 US claimed
EP-0034430-A1 Process for preparing arylacetaldehydes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-26 EP claimed
US-4248779-A REACTING CARBONYL SULFIDE WITH A SECONDARY AMINE AND REACTING THE AMINE SALT WITH A HALOHYDROCARBON IHARA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 1981-02-03 US claimed
EP-4698519-A1 3,5-DIAMINOTRIAZOLE DERIVATIVES AND USES THEREOF FOR TREATING OCULAR DISEASES Centre National de la Recherche Scientifique (FR) 2026-02-25 EP disclosed
US-20250223514-A1 CLEANSING COMPOSITION FOR WAFER DICING SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-07-10 US disclosed
CN-119708044-A Andrographolide derivative containing thiazolidine ketone heterocycle, preparation method and application thereof 西北农林科技大学 2025-03-28 CN disclosed
WO-2025060974-A1 N-SULFONYL CARBOXAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海宇道生物技术有限公司 2025-03-27 WO disclosed
US-4118561-A ANTIBACTERIAL, SYNERGISTIC, ANTI-CANCER ACTIVITY, ANTI-FOLIC ACID ACTIVITY AMERICAN HOME PRODUCTS CORPORATION (US) 1978-10-03 US disclosed
US-4060690-A COBALT CONTAINING CATALYST DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed
US-4002769-A INHIBITING ECLOSION OF FLY AND MOSQUITO PUPAE WITH ARYLTERPENOIDS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-01-11 US disclosed
US-3974202-A CARBON MONOXIDE, BENZYL HALIDE AND AN ALCOHOL; COBALT OR IRON CARBONYL CATALYST DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed