Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Chloromethyl)Benzene SCHEMBL28389405 | 0.84 | TSHR (0.42) | TSHRHTR2ASLC6A2SLC6A3ADRB2 | |
| SCHEMBL51783 | 0.82 | IDO1 (0.52) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL2865480 | 0.81 | ADRB2 (0.41) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL11031906 | 0.80 | IDO1 (0.50) | L3MBTL1FAAHIDO1ALDH1A1HTT | |
| SCHEMBL8750481 | 0.80 | TSHR (0.64) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL30702238 | 0.80 | IDO1 (0.50) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL31496031 | 0.80 | IDO1 (0.50) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL5655554 | 0.79 | TSHR (0.46) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL23040222 | 0.78 | TSHR (0.40) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL18459491 | 0.78 | ADRB2 (0.56) | TSHRMAPK1ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171814-A1 | Polymer | HALL RICHARD H | 2008-07-17 | — | — | US | claimed |
| JP-2001072622-A | PRODUCTION OF CHLOROMETHYLSTYRENES | NIPPON LIGHT METAL CO LTD | 2001-03-21 | — | — | JP | disclosed |
| US-4260826-A | PHOSPHONIUM CATIONIC SURFACTANTS | THE DOW CHEMICAL COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4240982-A | CONTAINING ETHER OR POLYETHER COMPONENT | THE DOW CHEMICAL COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| US-4175196-A | Certain pyridinium surfactants | THE DOW CHEMICAL COMPANY (US) | 1979-11-20 | — | — | US | disclosed |
| US-4093663-A | Novel onium surfactants | THE DOW CHEMICAL COMPANY (US) | 1978-06-06 | — | — | US | disclosed |