Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 12/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.65 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.65 |
| ▸ | HRH1 | P35367 | 2/20 | 0.65 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desfesoterodine SCHEMBL3924814 | 1.00 | CHRM3 (0.65) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Desfesoterodine SCHEMBL1808422 | 0.92 | CHRM2 (0.68) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Desfesoterodine SCHEMBL1808420 | 0.92 | CHRM2 (0.68) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Desfesoterodine SCHEMBL1811715 | 0.92 | CHRM2 (0.68) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Desfesoterodine SCHEMBL28757704 | 0.91 | CHRM3 (0.66) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Desfesoterodine SCHEMBL816124 | 0.91 | CHRM3 (0.72) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Desfesoterodine SCHEMBL209062 | 0.91 | CHRM3 (0.72) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Desfesoterodine SCHEMBL29468683 | 0.91 | CHRM3 (0.72) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Desfesoterodine SCHEMBL580657 | 0.91 | CHRM3 (0.72) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Desfesoterodine SCHEMBL14696972 | 0.88 | CHRM2 (0.62) | CHRM3ADRB2CHRM2CHRM1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019358-B2 | 3,3-DIARYLPROPYLAMINES , THEIR USE AND PREPARATION | PFIZER HEALTH AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| US-6313132-B1 | FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER | PHARMACIA AB (SE) | 2001-11-06 | — | — | US | disclosed |