Desfesoterodine

Desfesoterodine

SCHEMBL816124

CC(C)N(CC[C@@H](c1ccccc1)c1cc(CO)ccc1O)C(C)C

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 12/20 0.72
CHRM2 P08172 3/20 0.72
CHRM1 P11229 3/20 0.72
CHRM5 P08912 2/20 0.72
HRH1 P35367 2/20 0.72
LMNA P02545 1/20 0.72
ESR1 P03372 1/20 0.72
CHRM4 P08173 1/20 0.72
MAPT P10636 1/20 0.72
KCNE1 P15382 1/20 0.72
PTGS1 P23219 1/20 0.72
HRH2 P25021 1/20 0.72
HTR2A P28223 1/20 0.72
SLC6A4 P31645 1/20 0.72
ADRA1A P35348 1/20 0.72
OPRK1 P41145 1/20 0.72
KCNQ1 P51787 1/20 0.72
KCNH2 Q12809 1/20 0.72
CACNA1C Q13936 1/20 0.72
SCN5A Q14524 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Desfesoterodine SCHEMBL580657 1.00 CHRM3 (0.72) CHRM3CHRM2CHRM1CHRM5HRH1
Desfesoterodine SCHEMBL29468683 1.00 CHRM3 (0.72) CHRM3CHRM2CHRM1CHRM5HRH1
Desfesoterodine SCHEMBL209062 1.00 CHRM3 (0.72) CHRM3CHRM2CHRM1CHRM5HRH1
Desfesoterodine SCHEMBL28757704 0.95 CHRM3 (0.66) CHRM3CHRM2CHRM1CHRM5HRH1
Desfesoterodine SCHEMBL1808420 0.94 CHRM2 (0.68) CHRM3CHRM2CHRM1CHRM5HRH1
Desfesoterodine SCHEMBL1811715 0.94 CHRM2 (0.68) CHRM3CHRM2CHRM1CHRM5HRH1
Desfesoterodine SCHEMBL1808422 0.94 CHRM2 (0.68) CHRM3CHRM2CHRM1CHRM5HRH1
Desfesoterodine SCHEMBL14696972 0.92 CHRM2 (0.62) CHRM3CHRM2CHRM1CHRM5HRH1
SCHEMBL27490008 0.91 CHRM3 (0.60) CHRM3CHRM2CHRM1CHRM5HRH1
SCHEMBL27491771 0.91 CHRM3 (0.60) CHRM3CHRM2CHRM1CHRM5HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3104848-B1 INHALABLE PARTICLE FORMULATIONS COMPRISING AN ANTIMUSCARINIC AGENT CRYSTEC LTD (GB) 2020-05-06 EP claimed
US-20110105783-A1 PROCESS FOR THE PREPARATION OF FESOTERODINE DIPHARMA FRANCIS S.R.I. (IT) 2011-05-05 US claimed
EP-2316817-A1 Process for the preparation of fesoterodine Dipharma Francis S.r.l. (IT) 2011-05-04 EP claimed
US-11759420-B2 Inhalable particles CRYSTEC LTD (GB) 2023-09-19 US disclosed
US-20220331243-A1 INHALABLE PARTICLES CRYSTEC LTD (GB) 2022-10-20 US disclosed
US-11351115-B2 Inhalable particles CRYSTEC LTD (GB) 2022-06-07 US disclosed
US-20170056325-A1 Improvements Relating To Inhalable Particles CRYSTEC LTD (GB) 2017-03-02 US disclosed
US-20150306170-A1 COMPOSITION FOR IMMEDIATE AND EXTENDED RELEASE FERRING B.V. (NL) 2015-10-29 US disclosed
EP-2922525-A1 COMPOSITION FOR IMMEDIATE AND EXTENDED RELEASE Ferring BV (NL) 2015-09-30 EP disclosed
WO-2014079922-A1 COMPOSITION FOR IMMEDIATE AND EXTENDED RELEASE FERRING B.V. (NL) 2014-05-30 WO disclosed
US-8530691-B2 Process for the preparation of fesoterodine DIPHARMA FRANCIS S.R.L. (IT) 2013-09-10 US disclosed
US-20030144352-A1 Antimuscarinic aerosol PHARMACIA & UPJOHN COMPANY 2003-07-31 US disclosed
US-20030118633-A1 Combination therapy PHARMACIA AB (SE) 2003-06-26 US disclosed
WO-2003039524-A1 ANTI-MUSCARINIC AGENT AND ESTROGEN-AGONIST FOR TREATING UNSTABLE OR OVERACTIVE BLADDER PHARMACIA AB (SE) 2003-05-15 WO disclosed
EP-1254890-A1 Derivatives of 3,3-diphenylpropylamines SCHWARZ PHARMA AG (DE) 2002-11-06 EP disclosed
EP-1077912-B1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SANOL ARZNEI SCHWARZ GMBH (DE) 2002-07-03 EP disclosed
EP-1128819-A1 NEW CONTROLLED RELEASE BEAD, A METHOD OF PRODUCING THE SAME AND MULTIPLE UNIT FORMULATION COMPRISING IT Pharmacia AB (SE) 2001-09-05 EP disclosed
EP-1077912-A1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2001-02-28 EP disclosed
WO-2000027364-A1 NEW CONTROLLED RELEASE BEAD, A METHOD OF PRODUCING THE SAME AND MULTIPLE UNIT FORMULATION COMPRISING IT PHARMACIA AB (SE) 2000-05-18 WO disclosed
WO-1999058478-A1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 1999-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105783-A1 PROCESS FOR THE PREPARATION OF FESOTERODINE HADHB, MAOB, FOSB CHRM3 293/4885CHRM2 558/4885CHRM1 677/4885
US-20030144352-A1 Antimuscarinic aerosol CHRM3, CHRM1, CHRM5 CHRM3 1/4885CHRM2 4/4885CHRM1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.