Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16824925 | 0.81 | ACP3 (0.51) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL1960513 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL6691324 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL9137122 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL16651165 | 0.75 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL812445 | 0.75 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL809480 | 0.75 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL14478233 | 0.74 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL8084818 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1317230 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791811-A1 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| EP-1697301-A2 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2006033446-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2006-03-30 | — | — | WO | disclosed |
| WO-2005061433-A2 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |