Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960513 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9137122 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8084818 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL28372644 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5703968 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL27298149 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4743348 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8003498 | 0.77 | CA1 (0.66) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9300709 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL28285992 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439943-A | Non-steroid and non-prostanoid inhibitors of steroid and prostaglandin transforming enzymes | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-08-08 | — | — | US | claimed |
| US-5399790-A | Non-steroid and non-prostanoid inhibitors of steroid and prostaglandin transforming enzymes | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-03-21 | — | — | US | claimed |
| US-5258296-A | Non-steroid and non-prostanoid inhibitors of steroid and prostaglandin transfroming enzymes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1993-11-02 | — | — | US | claimed |
| US-5118621-A | Non-steroidal suicide substrates of hydroxysteroid dehydrogenase | UNIVERSITY OF PENNSYLVANIA (US) | 1992-06-02 | — | — | US | claimed |
| EP-4359375-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS | McMaster University (CA) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022266765-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2022-12-29 | — | — | WO | disclosed |
| US-20040214798-A1 | Nitroaryl phosphoramide compositions and methods for targeting and inhibiting undesirable cell growth or proliferation | HU, LONGQIN | 2004-10-28 | — | — | US | disclosed |
| US-5439943-A | Non-steroid and non-prostanoid inhibitors of steroid and prostaglandin transforming enzymes | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-08-08 | — | — | US | disclosed |
| US-5439943-A | Non-steroid and non-prostanoid inhibitors of steroid and prostaglandin transforming enzymes | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-08-08 | — | — | US | disclosed |
| US-5399790-A | Non-steroid and non-prostanoid inhibitors of steroid and prostaglandin transforming enzymes | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-03-21 | — | — | US | disclosed |
| US-5399790-A | Non-steroid and non-prostanoid inhibitors of steroid and prostaglandin transforming enzymes | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-03-21 | — | — | US | disclosed |
| US-5258296-A | Non-steroid and non-prostanoid inhibitors of steroid and prostaglandin transfroming enzymes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1993-11-02 | — | — | US | disclosed |
| US-5258296-A | Non-steroid and non-prostanoid inhibitors of steroid and prostaglandin transfroming enzymes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1993-11-02 | — | — | US | disclosed |
| US-5118621-A | Non-steroidal suicide substrates of hydroxysteroid dehydrogenase | UNIVERSITY OF PENNSYLVANIA (US) | 1992-06-02 | — | — | US | disclosed |
| US-5118621-A | Non-steroidal suicide substrates of hydroxysteroid dehydrogenase | UNIVERSITY OF PENNSYLVANIA (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0422897-A2 | Recovery of water-insoluble epoxy alcohols | ARCO Chemical Technology, L.P. (US) | 1991-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214798-A1 | Nitroaryl phosphoramide compositions and methods for targeting and inhibiting undesirable cell growth or proliferation | MKI67, NME2, NTPCR | ALDH1A1 2164/4885MAPT 4367/4885MEN1 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.