SCHEMBL517865

SCHEMBL517865

CC(C)(C)[Si](C)(C)OC(CCCCCCCC(=O)O)CCCCCCCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.42
FFAR1 O14842 2/20 0.42
ALDH1A1 P00352 4/20 0.41
TSHR P16473 5/20 0.40
LMNA P02545 1/20 0.40
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
GSTK1 Q9Y2Q3 1/20 0.40
GPR84 Q9NQS5 7/20 0.38
PPARG P37231 6/20 0.38
PPARD Q03181 6/20 0.38
PPARA Q07869 6/20 0.38
HDAC11 Q96DB2 5/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38
PTPN1 P18031 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9461433 0.94 FFAR4 (0.53) FFAR4FFAR1ALDH1A1TSHRLMNA
SCHEMBL2563715 0.94 FFAR4 (0.53) FFAR4FFAR1ALDH1A1TSHRLMNA
SCHEMBL18540778 0.94 FFAR4 (0.53) FFAR4FFAR1ALDH1A1TSHRLMNA
SCHEMBL2563716 0.94 FFAR4 (0.53) FFAR4FFAR1ALDH1A1TSHRLMNA
SCHEMBL18665683 0.94 GPR84 (0.47) FFAR4FFAR1ALDH1A1TSHRLMNA
SCHEMBL28725173 0.88 FFAR4 (0.45) FFAR4FFAR1ALDH1A1TSHRGPR84
SCHEMBL16669141 0.83 FFAR4 (0.39) FFAR4FFAR1ALDH1A1TSHRLMNA
SCHEMBL24305225 0.82 FFAR4 (0.43) FFAR4FFAR1ALDH1A1TSHRGPR84
SCHEMBL26733224 0.82 FFAR4 (0.43) FFAR4FFAR1ALDH1A1TSHRGPR84
SCHEMBL17743872 0.81 FFAR1 (0.58) FFAR4FFAR1ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674856-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2026-01-07 EP disclosed
EP-2788006-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2026-01-07 EP disclosed
EP-3254672-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2025-08-20 EP disclosed
US-12364762-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-07-22 US disclosed
US-12350338-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-07-08 US disclosed
US-12343398-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-07-01 US disclosed
US-12239709-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-03-04 US disclosed
EP-4481047-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2024-12-25 EP disclosed
US-20240398956-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2024-12-05 US disclosed
US-20240285767-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2024-08-29 US disclosed
US-9012498-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-04-21 US disclosed
EP-2788006-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2014-10-15 EP disclosed
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-08-01 US disclosed
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-08-01 US disclosed
WO-2013086354-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-06-13 WO disclosed
WO-2013086354-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-06-13 WO disclosed
EP-2575764-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2013-04-10 EP disclosed
US-20120027803-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2012-02-02 US disclosed
WO-2011153493-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2011-12-08 WO disclosed
WO-2011153493-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2011-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120027803-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, CETP, APOB FFAR4 418/4885FFAR1 491/4885ALDH1A1 2749/4885
US-12343398-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP FFAR4 625/4885FFAR1 641/4885ALDH1A1 3151/4885
US-20240398956-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP FFAR4 625/4885FFAR1 641/4885ALDH1A1 3151/4885
US-12350338-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP FFAR4 625/4885FFAR1 641/4885ALDH1A1 3151/4885
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP FFAR4 625/4885FFAR1 641/4885ALDH1A1 3151/4885
US-20240285767-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP FFAR4 625/4885FFAR1 641/4885ALDH1A1 3151/4885
US-12239709-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP FFAR4 625/4885FFAR1 641/4885ALDH1A1 3151/4885
US-12364762-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP FFAR4 625/4885FFAR1 641/4885ALDH1A1 3151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.