SCHEMBL5178804

SCHEMBL5178804

CCCCCC(=O)O[Si](OCC)(OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.48
LMNA P02545 3/20 0.46
PAM P19021 2/20 0.44
CES2 O00748 4/20 0.43
CES1 P23141 4/20 0.43
MAPT P10636 2/20 0.43
MAPK1 P28482 1/20 0.43
TSHR P16473 2/20 0.42
AKR1B1 P15121 1/20 0.41
HSP90AA1 P07900 1/20 0.41
ALDH1A1 P00352 2/20 0.41
DNM1 Q05193 1/20 0.41
NAAA Q02083 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
PPARG P37231 1/20 0.40
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1517686 0.98 DGKA (0.52) DGKALMNAPAMCES2CES1
SCHEMBL28286997 0.96 DGKA (0.50) DGKALMNAPAMCES2CES1
SCHEMBL28293756 0.96 DGKA (0.50) DGKALMNAPAMCES2CES1
SCHEMBL6243475 0.94 DGKA (0.52) DGKALMNAPAMCES2CES1
SCHEMBL28026117 0.94 CES1 (0.41) DGKALMNAPAMCES2CES1
SCHEMBL8679524 0.85 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL3918624 0.85 ALDH1A1 (0.48) DGKALMNACES2CES1TSHR
SCHEMBL9012985 0.85 CYP1A2 (0.50) DGKALMNAPAMMAPTTSHR
SCHEMBL12504164 0.82 DGKA (0.47) DGKALMNAPAMCES2CES1
SCHEMBL12504513 0.82 DGKA (0.47) DGKALMNAPAMCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6298829-A None JP disclosed
JP-6298828-A None JP disclosed
CN-105378615-B The manufacturing method of touch panel negative-type photosensitive white composition, touch panel and touch panel 东丽株式会社 2019-05-31 CN disclosed
EP-1791891-A1 SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF Phosphonics LTD (GB) 2007-06-06 EP disclosed
WO-2006013080-A1 SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF PHOSPHONICS LTD (GB) 2006-02-09 WO disclosed
JP-H06298829-A PRODUCTION OF PROPYLENE BLOCK COPOLYMER TONEN CORP 1994-10-25 JP disclosed
JP-H06298828-A PRODUCTION OF PROPYLENE BLOCK COPOLYMER TONEN CORP 1994-10-25 JP disclosed