Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690377 | 0.86 | PIN1 (0.58) | PIN1FAAHPRF1CHEK2PARP1 | |
| SCHEMBL4239948 | 0.79 | MAPKAPK2 (0.47) | PIN1CHEK2MAPTMEN1KMT2A | |
| SCHEMBL30732472 | 0.79 | CHEK2 (0.47) | CHEK2MAPTLCK | |
| SCHEMBL29414225 | 0.78 | KMT2A (0.46) | FAAHCHEK2MAPTMEN1KMT2A | |
| SCHEMBL16268186 | 0.78 | MAPT (0.37) | PIN1FAAHCCND3CDK6CHEK2 | |
| SCHEMBL30707784 | 0.78 | HRH4 (0.44) | FAAHCHEK2CYP2C19JAK2GSK3B | |
| SCHEMBL9107283 | 0.78 | HRH4 (0.44) | FAAHCHEK2CYP2C19JAK2GSK3B | |
| SCHEMBL3064168 | 0.78 | KMT2A (0.46) | FAAHCHEK2MAPTMEN1KMT2A | |
| SCHEMBL30707844 | 0.78 | PIN1 (0.55) | PIN1CHEK2MAPTMEN1CYP1A2 | |
| SCHEMBL4742860 | 0.77 | ALDH1A1 (0.48) | MAPTMEN1KMT2ACYP3A4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |