SCHEMBL5179907

SCHEMBL5179907

C=CC[Si](CC=C)(OCCCC)OCCCC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.38
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ATM Q13315 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL460505 0.94 TSHR (0.34) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL460504 0.94 TSHR (0.34) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL1923064 0.93 TSHR (0.39) TSHRALDH1A1HPGD
SCHEMBL10920207 0.86 TSHR (0.32) TSHRALDH1A1HPGD
SCHEMBL3338598 0.86 TSHR (0.33) TSHRALDH1A1
SCHEMBL22654287 0.85 TSHR (0.37) TSHRALDH1A1HPGD
SCHEMBL15302202 0.82 TSHR (0.39) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL389689 0.82 TSHR (0.39) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL460978 0.80
SCHEMBL22654188 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014503-A1 GAS BARRIER FILM MATERIAL, SILICON OXIDE FILM, AND PRODUCTION METHOD OF SILICON OXIDE FILM 東ソー株式会社 2024-01-18 WO disclosed
WO-2022255290-A1 METHOD FOR MANUFACTURING PLANARIZING FILM, PLANARIZING FILM MATERIAL, AND PLANARIZING FILM 東ソー株式会社 2022-12-08 WO disclosed
WO-2022230944-A1 PLANARIZING FILM MANUFACTURING METHOD, PLANARIZING FILM MATERIAL, AND PLANARIZING FILM 東ソー株式会社 2022-11-03 WO disclosed
CN-103130825-B The manufacture method of 1,3 difluoro disiloxane compounds 株式会社艾迪科 2016-12-21 CN disclosed
US-8791221-B2 Addition-curable metallosiloxane compound DAICEL CORPORATION (JP) 2014-07-29 US disclosed
EP-2650319-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND Daicel Corporation (JP) 2013-10-16 EP disclosed
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND DAICEL CORPORATION (JP) 2013-10-10 US disclosed
CN-103249762-A Addition-curable metallosiloxane compound DAICEL CORP 2013-08-14 CN disclosed
CN-103130825-A 1,3-difluoro disiloxane compound manufacturing method ADEKA CORP 2013-06-05 CN disclosed
US-7291567-B2 Silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR CORPORATION (JP) 2007-11-06 US disclosed
US-7166362-B2 Film-forming composition, production process therefor, and porous insulating film FUJI PHOTO FILM CO., LTD. (JP) 2007-01-23 US disclosed
US-20060024980-A1 Silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR CORPORATION (JP) 2006-02-02 US disclosed
EP-1619226-A1 Silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR Corporation (JP) 2006-01-25 EP disclosed
US-20050074556-A1 Film-forming composition, production process therefor, and porous insulating film FUJI PHOTO FILM CO., LTD. 2005-04-07 US disclosed
US-6232376-B1 BLEND CONTAINING ORGANOSILICON COMPOUND, PEROXIDE, HINDERED AMINE STABILIZER AND ANTIOXIDANTS NIPPON UNICAR COMPANY LTD. (JP) 2001-05-15 US disclosed
US-4857250-A One-extrusion method of making a shaped crosslinkable extruded polymeric product UNION CARBIDE CORPORATION (US) 1989-08-15 US disclosed
EP-0235439-A1 Electrically conductive polymers and their production RAPRA TECHNOLOGY LIMITED (GB) 1987-09-09 EP disclosed
EP-0163865-A1 One-extrusion method for making a shaped crosslinked polymeric product UNION CARBIDE CORPORATION (US) 1985-12-11 EP disclosed
WO-1985004618-A1 ONE-EXTRUSION METHOD OF MAKING A SHAPED CROSSLINKABLE EXTRUDED POLYMERIC PRODUCT UNION CARBIDE CORPORATION (US) 1985-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND B2M, MSI2, MNS1 TSHR 4702/4885ALDH1A1 2073/4885HPGD 4532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.