SCHEMBL389689

SCHEMBL389689

C=CC[Si](OCCCC)(OCCCC)OCCCC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.38
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ATM Q13315 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2282793 0.96 TSHR (0.36) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL2286290 0.96 TSHR (0.36) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL2284144 0.94 TSHR (0.34) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL2285862 0.94 TSHR (0.34) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL3902659 0.93 TSHR (0.39) TSHRALDH1A1HPGD
SCHEMBL4579212 0.91 TSHR (0.43) TSHRALDH1A1
SCHEMBL9009705 0.91 TSHR (0.43) TSHRALDH1A1
SCHEMBL2286750 0.90 TSHR (0.34) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL2286889 0.90 TSHR (0.34) TSHRALDH1A1HPGDADRB2ADRB1
SCHEMBL29161772 0.86 TSHR (0.39) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101697-B2 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2012-01-24 US claimed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US claimed
EP-1549657-B1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES DOW CORNING (US) 2006-06-28 EP claimed
EP-1549657-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES Dow Corning Corporation (US) 2005-07-06 EP claimed
US-6878839-B2 Method for preparing organofunctional silanes DOW CORNING CORPORATION (US) 2005-04-12 US claimed
WO-2004033469-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES DOW CORNING CORPORATION (US) 2004-04-22 WO claimed
US-20040073053-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES DOW CORNING CORPORATION 2004-04-15 US claimed
US-4749727-A THREE-DIMENSIONAL CROSSLINKING; EPOXIDES, UNSATURATED ALKOXYSILANES; WATER CURABLE KANSAI PAINT CO., LTD. (JP) 1988-06-07 US claimed
EP-3715399-B1 FLUOROPOLYETHER-GROUP-CONTAINING POLYMER, SURFACE TREATMENT AGENT, AND ARTICLE SHINETSU CHEMICAL CO (JP) 2026-02-11 EP disclosed
EP-4585646-A1 FLUORINE-CONTAINING COMPOSITION, SURFACE TREATMENT AGENT, AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-07-16 EP disclosed
CN-119790105-A Fluorine-containing composition, surface treatment agent, and article 信越化学工业株式会社 2025-04-08 CN disclosed
WO-2025047304-A1 FLUOROPOLYETHER-GROUP-CONTAINING POLYMER, SURFACE-TREATING AGENT, AND ARTICLE 信越化学工業株式会社 2025-03-06 WO disclosed
CN-118843711-A Material for gas barrier film, silicon oxide film, and method for producing silicon oxide film 东曹株式会社 2024-10-25 CN disclosed
WO-2024190380-A1 SILICON-CONTAINING RESIN COMPOSITION PURIFIED PRODUCT MANUFACTURING METHOD, PATTERN FORMATION METHOD, AND SILICON-CONTAINING RESIN COMPOSITION PURIFIED PRODUCT 東京応化工業株式会社 2024-09-19 WO disclosed
US-4618389-A ALKENYLTRITHYDROCARBONOXYSILANE SWS SILICONES CORPORATION (US) 1986-10-21 US disclosed
EP-0124865-A2 A process for bonding heat curable silicone rubber to a substrate using an aqueous primer composition Wacker Silicones Corporation (US) 1984-11-14 EP disclosed
US-4349603-A THERMOPLASTIC RESIN HAVING A PRIMER COATING OF UNSATURATED SILANEDI-OR TRIOL/GRAFTED SYNTHETIC RUBBER AND AN EXTERIOR COATING OF A CR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-09-14 US disclosed
US-4260552-A INSECTICIDES, HERBICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4228092-A BY ALCOHOL ESTERIFICATION DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-10-14 US disclosed
US-4160846-A Method for controlling insects with tetrasubstituted organotin compounds UNIROYAL, INC. (US) 1979-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040073053-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES MSMO1, ADH1A, ADH1C TSHR 3849/4885ALDH1A1 86/4885HPGD 1222/4885
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers VCL, PUF60, JMJD6 TSHR 4359/4885ALDH1A1 3595/4885HPGD 2321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.