SCHEMBL1923064

SCHEMBL1923064

C=CC[Si](CC=C)(OCCCCC)OCCCCC

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.39
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.32
PLA2G2C Q5R387 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
CA12 O43570 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5179907 0.93 TSHR (0.39) TSHRALDH1A1HPGD
SCHEMBL22654287 0.92 TSHR (0.37) TSHRALDH1A1HPGD
SCHEMBL460505 0.88 TSHR (0.34) TSHRALDH1A1HPGD
SCHEMBL460504 0.88 TSHR (0.34) TSHRALDH1A1HPGD
SCHEMBL3338598 0.84 TSHR (0.33) TSHRALDH1A1
SCHEMBL3902659 0.83 TSHR (0.39) TSHRALDH1A1HPGDPLA2G2CCA1
SCHEMBL9252663 0.83 TSHR (0.39) TSHRALDH1A1HPGDPLA2G2CCA1
SCHEMBL9009705 0.81 TSHR (0.43) TSHRALDH1A1PLA2G2CCA1CA2
SCHEMBL22654290 0.81 TSHR (0.38) TSHRALDH1A1HPGD
SCHEMBL4579212 0.81 TSHR (0.43) TSHRALDH1A1PLA2G2CCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373550-A1 METHOD OF PREPARING SUPPORTED LIPID FILM MEMBRANES AND USE THEREOF Biacore AB (SE) 2004-01-02 EP claimed
US-20020182717-A1 Method of preparing supported lipid film membranes and use thereof BIACORE AB (SE) 2002-12-05 US claimed
WO-2002072873-A1 METHOD OF PREPARING SUPPORTED LIPID FILM MEMBRANES AND USE THEREOF BIACORE AB (SE) 2002-09-19 WO claimed
EP-0483465-B1 Long chain di(acyloxy)dialkylsilanes, di(acyloxy)diarylsilanes, di(acyloxy)dialkoxysilanes, and tetra(acyloxy)silanes, process for their preparation, their use for the preparation of vesicles, so produced vesicles and their use as vehicles for drugs SALAMA ZOSER BOULIS DR (DE) 1995-08-02 EP claimed
EP-0483465-A1 Long chain di(acyloxy)dialkylsilanes, di(acyloxy)diarylsilanes, di(acyloxy)dialkoxysilanes, and tetra(acyloxy)silanes, process for their preparation, their use for the preparation of vesicles, so produced vesicles and their use as vehicles for drugs Salama, Zoser Boulis, Dr. (DE) 1992-05-06 EP claimed
US-11912889-B2 Silicon-containing polymer, film-forming composition, method for forming silicon-containing polymer coating, method for forming silica coating, and production method for silicon-containing polymer TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-27 US disclosed
US-20220220338-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR FORMING SILICON-CONTAINING POLYMER COATING, METHOD FOR FORMING SILICA COATING, AND PRODUCTION METHOD FOR SILICON-CONTAINING POLYMER TOKYO OHKA KOGYO CO., LTD. (JP) 2022-07-14 US disclosed
US-20220213348-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR SUPPORTING METAL COMPOUND ON SURFACE OF OBJECT TO BE TREATED, ARTICLE HAVING METAL COMPOUND-SUPPORTING COATING FILM, AND METHOD FOR PRODUCING SILICON-CONTAINING POLYMER TOKYO OHKA KOGYO CO., LTD. (JP) 2022-07-07 US disclosed
US-11377522-B2 Silicon-containing polymer, film-forming composition, method for forming silicon-containing polymer coating, method for forming silica-based coating, and production method for silicon-containing polymer TOKYO OHKA KOGYO CO., LTD. (JP) 2022-07-05 US disclosed
EP-3971229-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR FORMING SILICON-CONTAINING POLYMER COATING, METHOD FOR FORMING SILICA COATING, AND PRODUCTION METHOD FOR SILICON-CONTAINING POLYMER TOKYO OHKA KOGYO CO., LTD. (JP) 2022-03-23 EP disclosed
EP-3957678-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR SUPPORTING METAL COMPOUND ON SURFACE OF OBJECT TO BE TREATED, ARTICLE HAVING METAL COMPOUND-SUPPORTING COATING FILM, AND METHOD FOR PRODUCING SILICON-CONTAINING POLYMER Tokyo Ohka Kogyo Co., Ltd. (JP) 2022-02-23 EP disclosed
US-11241393-B2 Organosilicon carriers for use in treating infections and/or diseases caused by SARS viruses SALAMA ZOSER B (DE) 2022-02-08 US disclosed
EP-1188058-A2 METHOD AND APPARATUS FOR ASSAYING A DRUG CANDIDATE TO ESTIMATE A PHARMACOKINETIC PARAMETER ASSOCIATED THEREWITH Biacore AB (SE) 2002-03-20 EP disclosed
US-20020019019-A1 Method and apparatus for assaying a drug candidate to estimate a pharmacokinetic parameter associated therewith GE HEALTHCARE BIO-SCIENCES AB (SE) 2002-02-14 US disclosed
WO-2000079268-A2 METHOD AND APPARATUS FOR ASSAYING A DRUG CANDIDATE TO ESTIMATE A PHARMACOKINETIC PARAMETER ASSOCIATED THEREWITH BIACORE AB (SE) 2000-12-28 WO disclosed
EP-0483465-B1 Long chain di(acyloxy)dialkylsilanes, di(acyloxy)diarylsilanes, di(acyloxy)dialkoxysilanes, and tetra(acyloxy)silanes, process for their preparation, their use for the preparation of vesicles, so produced vesicles and their use as vehicles for drugs SALAMA ZOSER BOULIS DR (DE) 1995-08-02 EP disclosed
EP-0483465-B1 Long chain di(acyloxy)dialkylsilanes, di(acyloxy)diarylsilanes, di(acyloxy)dialkoxysilanes, and tetra(acyloxy)silanes, process for their preparation, their use for the preparation of vesicles, so produced vesicles and their use as vehicles for drugs SALAMA ZOSER BOULIS DR (DE) 1995-08-02 EP disclosed
EP-0483465-A1 Long chain di(acyloxy)dialkylsilanes, di(acyloxy)diarylsilanes, di(acyloxy)dialkoxysilanes, and tetra(acyloxy)silanes, process for their preparation, their use for the preparation of vesicles, so produced vesicles and their use as vehicles for drugs Salama, Zoser Boulis, Dr. (DE) 1992-05-06 EP disclosed
EP-0483465-A1 Long chain di(acyloxy)dialkylsilanes, di(acyloxy)diarylsilanes, di(acyloxy)dialkoxysilanes, and tetra(acyloxy)silanes, process for their preparation, their use for the preparation of vesicles, so produced vesicles and their use as vehicles for drugs Salama, Zoser Boulis, Dr. (DE) 1992-05-06 EP disclosed
EP-0483465-A1 Long chain di(acyloxy)dialkylsilanes, di(acyloxy)diarylsilanes, di(acyloxy)dialkoxysilanes, and tetra(acyloxy)silanes, process for their preparation, their use for the preparation of vesicles, so produced vesicles and their use as vehicles for drugs Salama, Zoser Boulis, Dr. (DE) 1992-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11241393-B2 Organosilicon carriers for use in treating infections and/or diseases caused by SARS viruses ACE2, ACE, TMPRSS2 TSHR 2747/4885ALDH1A1 3096/4885HPGD 3252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.