SCHEMBL51801

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11548327	0.86	MAOB (0.54)	CYP1B1MAPTMAOBPLIN1LMNA
	SCHEMBL11548296	0.84	AKR1C1 (0.47)	CYP1B1MAPTMAOBPLIN1LMNA
	Maleic Acid SCHEMBL9395668	0.83	CYP3A4 (0.59)	CYP1B1MAPTMAOBPLIN1LMNA
	SCHEMBL4614478	0.83	CYP1B1 (0.55)	CYP1B1MAPTMAOBPLIN1LMNA
	SCHEMBL4614472	0.83	CYP1B1 (0.55)	CYP1B1MAPTMAOBPLIN1LMNA
	SCHEMBL28345700	0.83	MAPT (0.50)	CYP1B1MAPTMAOBPLIN1LMNA
	SCHEMBL11574955	0.82	MAPT (0.53)	CYP1B1MAPTMAOBPLIN1LMNA
	SCHEMBL4613759	0.81	ALDH1A1 (0.45)	CYP1B1MAPTMAOBPLIN1LMNA
	SCHEMBL4817483	0.81	HDAC3 (0.54)	CYP1B1MAPTMAOBPLIN1LMNA
	SCHEMBL6420549	0.81	ALDH1A1 (0.45)	CYP1B1MAPTMAOBPLIN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.