Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179893 | 1.00 | DNM1 (0.50) | DNM1GNAI3GNAO1GNAI1DGKA | |
| SCHEMBL5178119 | 0.94 | GNAI3 (0.51) | DNM1GNAI3GNAO1GNAI1DGKA | |
| SCHEMBL5178032 | 0.94 | GNAI3 (0.51) | DNM1GNAI3GNAO1GNAI1DGKA | |
| SCHEMBL5179896 | 0.93 | GNAI3 (0.53) | DNM1GNAI3GNAO1GNAI1DGKA | |
| SCHEMBL5179869 | 0.93 | GNAI3 (0.53) | DNM1GNAI3GNAO1GNAI1DGKA | |
| SCHEMBL5179404 | 0.83 | DNM1 (0.47) | DNM1GNAI3GNAO1GNAI1DGKA | |
| SCHEMBL5177904 | 0.81 | DNM1 (0.48) | DNM1GNAI3GNAO1GNAI1DGKA | |
| SCHEMBL5180334 | 0.81 | DNM1 (0.48) | DNM1GNAI3GNAO1GNAI1DGKA | |
| SCHEMBL5178169 | 0.81 | DNM1 (0.45) | DNM1GNAI3GNAO1GNAI1DGKA | |
| SCHEMBL5179258 | 0.81 | DNM1 (0.45) | DNM1GNAI3GNAO1GNAI1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927174-B1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MEDIGENE AG (DE) | 2007-12-12 | — | — | EP | disclosed |